RegulonDB

RegulonDB RegulonDB 10.7: Gene Form

relB gene in Escherichia coli K-12 genome

Gene local context to scale (view description)

Gene
Name:	relB
Synonym(s):	ECK1558, EG10836, RC, b1564
Genome position(nucleotides):	1645633 <-- 1645872 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	47.08
External database links:

ASAP:	ABE-0005224
CGSC:	305
ECHOBASE:	EB0829
OU-MICROARRAY:	b1564
PORTECO:	relB
REGULONDB:	b1564
STRING:	511145.b1564
M3D:	relB
COLOMBOS:	relB
PortEco:	b1564

Product

Name:

Qin prophage; antitoxin/DNA-binding transcriptional repressor RelB

Synonym(s):

Qin prophage, antitoxin RelB, Qin prophage, antitoxin of the RelE-RelB toxin-antitoxin system and DNA binding transcriptional repressor RelB, RelB

Sequence:

Get amino acid sequence Fasta Format

Regulator Family:

RelB, RelE

Cellular location:

cytosol

Molecular weight:

9.071

Isoelectric point:

4.52

Motif(s):

Type	Positions	Sequence
	1 -> 78	MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLRNPKPVRVTLDE
	7 -> 7	R
	45 -> 45	P
	13 -> 13	K
	8 -> 8	I

Classification:

Multifun Terms (GenProtEC)
		2 - information transfer --> 2.2 - RNA related --> 2.2.2 - Transcription related
		2 - information transfer --> 2.2 - RNA related --> 2.2.4 - RNA degradation
		3 - regulation --> 3.1 - type of regulation --> 3.1.2 - transcriptional level --> 3.1.2.3 - repressor
		3 - regulation --> 3.1 - type of regulation --> 3.1.3 - posttranscriptional --> 3.1.3.1 - translation attenuation and efficiency
		3 - regulation --> 3.3 - genetic unit regulated --> 3.3.1 - operon
		5 - cell processes --> 5.6 - protection --> 5.6.3 - cell killing
Gene Ontology Terms (GO)
	cellular_component	GO:0005829 - cytosol
	molecular_function	GO:0003677 - DNA binding GO:0005515 - protein binding GO:0000986 - bacterial-type cis-regulatory region sequence-specific DNA binding
	biological_process	GO:0006351 - transcription, DNA-templated GO:0006355 - regulation of transcription, DNA-templated GO:0045892 - negative regulation of transcription, DNA-templated

External database links:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

PANTHER:

PDB:

PDB:

PDB:

PFAM:

PRIDE:

PRODB:

PROTEINMODELPORTAL:

REFSEQ:

SMR:

UNIPROT:

Operon

Name:

relBE-hokD

Operon arrangement:

Transcription unit	Promoter
relBE-hokD	relBp

Transcriptional Regulation
	Display Regulation
Repressed by:	RelB, RelB-RelE

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	TSS_1865	1645901		reverse	nd	[RS-EPT-CBR]	[1]
	promoter	TSS_1866	1646073		reverse	nd	[RS-EPT-CBR]	[1]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Reference(s)

[1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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