RegulonDB RegulonDB 10.8: Gene Form
   

sdhC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

sdhA sdhC sdhD ybgU ybgV CRP ArcA ArcA ArcA Fur CRP IHF ArcA ArcA ArcA TSS_842 TSS_842 TSS_841 TSS_841 TSS_840 TSS_840 sdhDp2 sdhDp2 sdhCp sdhCp gltAp1 gltAp1 TSS_839 TSS_839

Gene      
Name: sdhC    Texpresso search in the literature
Synonym(s): ECK0710, EG10933, b0721, cybA, cybL, dhsC
Genome position(nucleotides): 755177 --> 755566 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
49.23
External database links:  
ASAP:
ABE-0002460
CGSC:
17902
ECHOBASE:
EB0926
OU-MICROARRAY:
b0721
PortEco:
sdhC
STRING:
511145.b0721
COLOMBOS: sdhC


Product      
Name: succinate:quinone oxidoreductase, membrane protein SdhC
Synonym(s): CybA, CybL, DhsC, SdhC, large subunit of cytochrome b556
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 14.299
Isoelectric point: 10.452
Motif(s):
 
Type Positions Sequence
6 -> 123 KKQRPVNLDLQTIRFPITAIASILHRVSGVITFVAVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFGYLEETFEAGKRSAKISFVITVVLSLL
27 -> 52 SILHRVSGVITFVAVGILLWLLGTSL
69 -> 89 FVKFIMWGILTALAYHVVVGI
109 -> 129 SAKISFVITVVLSLLAGVLVW

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.4 - TCA cycle
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.6 - aerobic respiration
  1 - metabolism --> 1.4 - energy production/transport --> 1.4.1 - electron donors
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.15 - large molecule carriers --> 1.6.15.1 - cytochromes
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
GO:0045281 - succinate dehydrogenase complex
molecular_function GO:0009055 - electron transfer activity
GO:0046872 - metal ion binding
GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors
GO:0008177 - succinate dehydrogenase (ubiquinone) activity
GO:0000104 - succinate dehydrogenase activity
GO:0020037 - heme binding
GO:0048039 - ubiquinone binding
biological_process GO:0006099 - tricarboxylic acid cycle
GO:0009060 - aerobic respiration
GO:0017004 - cytochrome complex assembly
GO:0022900 - electron transport chain
GO:0055114 - oxidation-reduction process
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-10837N
ECOCYC:
SDH-MEMB1
ECOLIWIKI:
b0721
INTERPRO:
IPR000701
INTERPRO:
IPR014314
INTERPRO:
IPR034804
INTERPRO:
IPR018495
MODBASE:
P69054
PDB:
2WU2
PDB:
2WU5
PDB:
2WP9
PDB:
2WDV
PDB:
2WDR
PDB:
2WDQ
PDB:
2AD0
PDB:
2ACZ
PDB:
1NEN
PDB:
1NEK
PDB:
2WS3
PFAM:
PF01127
PRIDE:
P69054
PRODB:
PRO_000023920
PROSITE:
PS01001
PROSITE:
PS01000
REFSEQ:
NP_415249
SMR:
P69054
UNIPROT:
P69054


Operon      
Name: sdhCDAB-sucABCD-sdhX         
Operon arrangement:
Transcription unit        Promoter
sdhCDAB-sucABCD-sdhX
sdhDAB
sucAB
sucABCD


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, Fur, ArcA
Repressed by: FNR, ArcA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_839 754683 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_840 755805 forward nd [RS-EPT-CBR] [1]
  promoter TSS_841 755883 forward nd [RS-EPT-CBR] [1]
  promoter TSS_842 756352 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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