RegulonDB RegulonDB 10.9: Gene Form
   

sdhC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

sdhA sdhC sdhD ybgU ybgV CRP ArcA ArcA ArcA Fur CRP IHF ArcA ArcA ArcA TSS_842 TSS_842 TSS_841 TSS_841 TSS_840 TSS_840 sdhDp2 sdhDp2 sdhCp sdhCp gltAp1 gltAp1 TSS_839 TSS_839

Gene      
Name: sdhC    Texpresso search in the literature
Synonym(s): ECK0710, EG10933, b0721, cybA, cybL, dhsC
Genome position(nucleotides): 755177 --> 755566 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
49.23
External database links:  
ASAP:
ABE-0002460
CGSC:
17902
ECHOBASE:
EB0926
ECOLIHUB:
sdhC
OU-MICROARRAY:
b0721
STRING:
511145.b0721
COLOMBOS: sdhC


Product      
Name: succinate:quinone oxidoreductase, membrane protein SdhC
Synonym(s): CybA, CybL, DhsC, SdhC, large subunit of cytochrome b556
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 14.299
Isoelectric point: 10.452
Motif(s):
 
Type Positions Sequence
6 -> 123 KKQRPVNLDLQTIRFPITAIASILHRVSGVITFVAVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFGYLEETFEAGKRSAKISFVITVVLSLL
27 -> 52 SILHRVSGVITFVAVGILLWLLGTSL
69 -> 89 FVKFIMWGILTALAYHVVVGI
109 -> 129 SAKISFVITVVLSLLAGVLVW

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.4 - TCA cycle
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.6 - aerobic respiration
  1 - metabolism --> 1.4 - energy production/transport --> 1.4.1 - electron donors
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.15 - large molecule carriers --> 1.6.15.1 - cytochromes
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
GO:0045281 - succinate dehydrogenase complex
molecular_function GO:0009055 - electron transfer activity
GO:0046872 - metal ion binding
GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors
GO:0008177 - succinate dehydrogenase (ubiquinone) activity
GO:0000104 - succinate dehydrogenase activity
GO:0020037 - heme binding
GO:0048039 - ubiquinone binding
biological_process GO:0006099 - tricarboxylic acid cycle
GO:0009060 - aerobic respiration
GO:0017004 - cytochrome complex assembly
GO:0022900 - electron transport chain
GO:0055114 - oxidation-reduction process
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-10837N
ECOCYC:
SDH-MEMB1
ECOLIWIKI:
b0721
INTERPRO:
IPR034804
INTERPRO:
IPR018495
INTERPRO:
IPR014314
INTERPRO:
IPR000701
MODBASE:
P69054
PDB:
2WU2
PDB:
2WU5
PDB:
2WS3
PDB:
2WP9
PDB:
2WDV
PDB:
2WDR
PDB:
2WDQ
PDB:
2AD0
PDB:
2ACZ
PDB:
1NEN
PDB:
1NEK
PFAM:
PF01127
PRIDE:
P69054
PRODB:
PRO_000023920
PROSITE:
PS01000
PROSITE:
PS01001
REFSEQ:
NP_415249
SMR:
P69054
UNIPROT:
P69054


Operon      
Name: sdhCDAB-sucABCD-sdhX         
Operon arrangement:
Transcription unit        Promoter
sdhCDAB-sucABCD-sdhX
sdhDAB
sucAB
sucABCD


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, Fur, ArcA
Repressed by: FNR, ArcA


Regulation by small RNA    
  Display Regulation
small RNA spf, rybB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_839 754683 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_840 755805 forward nd [RS-EPT-CBR] [1]
  promoter TSS_841 755883 forward nd [RS-EPT-CBR] [1]
  promoter TSS_842 756352 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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