RegulonDB RegulonDB 10.8: Gene Form
   

uvrB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

uvrB ybhK bioD ybhU bioC DnaA LexA DnaA DnaA DnaA LexA LexA DnaA DnaA LexA DnaA uvrBp1 uvrBp1 uvrBp2 uvrBp2 uvrBp3 uvrBp3

Gene      
Name: uvrB    Texpresso search in the literature
Synonym(s): ECK0768, EG11062, b0779, dar-1, dar-6
Genome position(nucleotides): 813526 --> 815547 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 53.56
External database links:  
ASAP:
 ABE-0002658
CGSC:
 20
ECHOBASE:
 EB1055
OU-MICROARRAY:
 b0779
PortEco:
 uvrB
STRING:
 511145.b0779
COLOMBOS: uvrB


Shine dalgarno      
Sequence: caactccttcAGGTAGcgactcATG


Product      
Name: excision nuclease subunit B
Synonym(s): UvrB
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 76.226
Isoelectric point: 4.889
Motif(s):
 
Type Positions Sequence
39 -> 46 GVTGSGKT
95 -> 96 YY
634 -> 667 QKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRE
431 -> 597 QVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDIL
477 -> 477 H

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.2 - degradation of macromolecules --> 1.2.2 - DNA
  2 - information transfer --> 2.1 - DNA related --> 2.1.4 - DNA repair
  2 - information transfer --> 2.1 - DNA related --> 2.1.5 - DNA degradation
  5 - cell processes --> 5.6 - protection --> 5.6.1 - radiation
  5 - cell processes --> 5.8 - SOS response
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009380 - excinuclease repair complex
molecular_function GO:0003677 - DNA binding
GO:0004518 - nuclease activity
GO:0005515 - protein binding
GO:0016787 - hydrolase activity
GO:0016887 - ATPase activity
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0009381 - excinuclease ABC activity
GO:0042802 - identical protein binding
biological_process GO:0006281 - DNA repair
GO:0006974 - cellular response to DNA damage stimulus
GO:0009432 - SOS response
GO:0009314 - response to radiation
GO:0006289 - nucleotide-excision repair
GO:0090305 - nucleic acid phosphodiester bond hydrolysis
Note(s): Note(s): ...[more].
External database links:  
DIP:
 DIP-48012N
ECOCYC:
 EG11062-MONOMER
ECOLIWIKI:
 b0779
INTERPRO:
 IPR014001
INTERPRO:
 IPR041471
INTERPRO:
 IPR036876
INTERPRO:
 IPR027417
INTERPRO:
 IPR024759
INTERPRO:
 IPR006935
INTERPRO:
 IPR004807
INTERPRO:
 IPR001943
INTERPRO:
 IPR001650
MINT:
 MINT-1244062
PANTHER:
 PTHR24029
PDB:
 1QOJ
PDB:
 1E52
PFAM:
 PF17757
PFAM:
 PF04851
PFAM:
 PF12344
PFAM:
 PF02151
PFAM:
 PF00271
PRIDE:
 P0A8F8
PRODB:
 PRO_000024199
PROSITE:
 PS51194
PROSITE:
 PS51192
PROSITE:
 PS50151
REFSEQ:
 NP_415300
SMART:
 SM00490
SMART:
 SM00487
SMR:
 P0A8F8
UNIPROT:
 P0A8F8


Operon      
Name: uvrB         
Operon arrangement:
Transcription unit        Promoter
uvrB
uvrB
uvrB


Transcriptional Regulation      
Display Regulation             
Repressed by: DnaA, LexA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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