RegulonDB RegulonDB 10.7: Gene Form
   

uvrB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

Gene      
Name: uvrB    Texpresso search in the literature
Synonym(s): ECK0768, EG11062, b0779, dar-1, dar-6
Genome position(nucleotides): 813526 --> 815547 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
53.56
External database links:  
ASAP:
ABE-0002658
CGSC:
20
ECHOBASE:
EB1055
OU-MICROARRAY:
b0779
PORTECO:
uvrB
REGULONDB:
b0779
STRING:
511145.b0779
M3D: uvrB
COLOMBOS: uvrB
PortEco: b0779


Shine dalgarno      
Sequence: caactccttcAGGTAGcgactcATG


Product      
Name: excision nuclease subunit B
Synonym(s): UvrB
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 76.226
Isoelectric point: 4.889
Motif(s):
 
Type Positions Sequence
39 -> 46 GVTGSGKT
95 -> 96 YY
634 -> 667 QKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRE
431 -> 597 QVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDIL
477 -> 477 H

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.2 - degradation of macromolecules --> 1.2.2 - DNA
  2 - information transfer --> 2.1 - DNA related --> 2.1.4 - DNA repair
  2 - information transfer --> 2.1 - DNA related --> 2.1.5 - DNA degradation
  5 - cell processes --> 5.6 - protection --> 5.6.1 - radiation
  5 - cell processes --> 5.8 - SOS response
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009380 - excinuclease repair complex
molecular_function GO:0003677 - DNA binding
GO:0004518 - nuclease activity
GO:0005515 - protein binding
GO:0016787 - hydrolase activity
GO:0016887 - ATPase activity
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0009381 - excinuclease ABC activity
GO:0042802 - identical protein binding
biological_process GO:0006281 - DNA repair
GO:0006974 - cellular response to DNA damage stimulus
GO:0009432 - SOS response
GO:0009314 - response to radiation
GO:0006289 - nucleotide-excision repair
GO:0090305 - nucleic acid phosphodiester bond hydrolysis
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-48012N
ECOCYC:
EG11062-MONOMER
ECOLIWIKI:
b0779
INTERPRO:
IPR041471
INTERPRO:
IPR001650
INTERPRO:
IPR027417
INTERPRO:
IPR036876
INTERPRO:
IPR001943
INTERPRO:
IPR004807
INTERPRO:
IPR006935
INTERPRO:
IPR014001
INTERPRO:
IPR024759
MINT:
MINT-1244062
PANTHER:
PTHR24029
PDB:
1QOJ
PDB:
1E52
PFAM:
PF12344
PFAM:
PF04851
PFAM:
PF02151
PFAM:
PF00271
PFAM:
PF17757
PRIDE:
P0A8F8
PRODB:
PRO_000024199
PROSITE:
PS51194
PROSITE:
PS51192
PROSITE:
PS50151
PROTEINMODELPORTAL:
P0A8F8
REFSEQ:
NP_415300
SMART:
SM00487
SMART:
SM00490
SMR:
P0A8F8
UNIPROT:
P0A8F8


Operon      
Name: uvrB         
Operon arrangement:
Transcription unit        Promoter
uvrB
uvrB
uvrB


Transcriptional Regulation      
Display Regulation             
Repressed by: DnaA, LexA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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