RegulonDB RegulonDB 10.7: Gene Form
   

ybgC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

tolQ tolR ybgC ybgE TSS_889 TSS_889 ybgCp5 ybgCp5 ybgCp6 ybgCp6

Gene      
Name: ybgC    Texpresso search in the literature
Synonym(s): ECK0725, EG11110, b0736
Genome position(nucleotides): 774752 --> 775156 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
49.63
External database links:  
ASAP:
ABE-0002508
ECHOBASE:
EB1101
OU-MICROARRAY:
b0736
PORTECO:
ybgC
REGULONDB:
b0736
STRING:
511145.b0736
M3D: ybgC
COLOMBOS: ybgC
PortEco: b0736


Product      
Name: esterase/thioesterase
Synonym(s): YbgC
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol,inner membrane
Molecular weight: 15.562
Isoelectric point: 7.658
Motif(s):
 
Type Positions Sequence
20 -> 103 GGVVYHASYVAFYERARTEMLRHHHFSQQALMAERVAFVVRKMTVEYYAPARLDDMLEIQTEITSMRGTSLVFTQRIVNAENTL

 

Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0016020 - membrane
GO:0005886 - plasma membrane
molecular_function GO:0005515 - protein binding
GO:0016787 - hydrolase activity
GO:0016790 - thiolester hydrolase activity
GO:0047617 - acyl-CoA hydrolase activity
biological_process GO:0006629 - lipid metabolic process
Note(s): Note(s): ...[more].
Evidence: [APPH] Assay of protein purified to homogeneity
Reference(s): [1] Kuznetsova E., et al., 2005
[2] Paradis-Bleau C., et al., 2014
External database links:  
DIP:
DIP-29375N
ECOCYC:
EG11110-MONOMER
ECOLIWIKI:
b0736
INTERPRO:
IPR014166
INTERPRO:
IPR008272
INTERPRO:
IPR006683
INTERPRO:
IPR006684
INTERPRO:
IPR029069
MINT:
MINT-1222012
MODBASE:
P0A8Z3
PDB:
5T07
PDB:
5T06
PDB:
5KL9
PDB:
1S5U
PFAM:
PF03061
PRIDE:
P0A8Z3
PROSITE:
PS01328
PROTEINMODELPORTAL:
P0A8Z3
REFSEQ:
NP_415264
SMR:
P0A8Z3
UNIPROT:
P0A8Z3


Operon      
Name: ybgC-tolQRA         
Operon arrangement:
Transcription unit        Promoter
ybgC-tolQRA
 


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter ybgCp6 774644 forward Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter ybgCp5 774709 forward Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter TSS_889 774711 forward nd [RS-EPT-CBR] [4]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Kuznetsova E., Proudfoot M., Sanders SA., Reinking J., Savchenko A., Arrowsmith CH., Edwards AM., Yakunin AF., 2005, Enzyme genomics: Application of general enzymatic screens to discover new enzymes., FEMS Microbiol Rev 29(2):263-79

 [2] Paradis-Bleau C., Kritikos G., Orlova K., Typas A., Bernhardt TG., 2014, A genome-wide screen for bacterial envelope biogenesis mutants identifies a novel factor involved in cell wall precursor metabolism., PLoS Genet 10(1):e1004056

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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