RegulonDB RegulonDB 10.8: Gene Form
   

ygeA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

araE lysA lysR ygeA anti-anti-terminator anti-terminator terminator ygeAp5 ygeAp5 TSS_3140 TSS_3140 lysAp lysAp lysRp lysRp

Gene      
Name: ygeA    Texpresso search in the literature
Synonym(s): ECK2838, EG11157, b2840
Genome position(nucleotides): 2979943 <-- 2980635 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
50.94
External database links:  
ASAP:
ABE-0009315
ECHOBASE:
EB1146
OU-MICROARRAY:
b2840
PortEco:
ygeA
STRING:
511145.b2840
COLOMBOS: ygeA


Product      
Name: amino acid racemase YgeA
Synonym(s): YgeA
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 25.248
Isoelectric point: 4.851
Motif(s):
 
Type Positions Sequence
198 -> 199 TE
7 -> 224 LGGMSWESTIPYYRLINEGIKQRLGGLHSAQVLLHSVDFHEIEECQRRGEWDKTGDILAEAALGLQRAGAEGIVLCTNTMHKVADAIESRCTLPFLHIADATGRAITGAGMTRVALLGTRYTMEQDFYRGRLTEQFSINCLIPEADERAKINQIIFEELCLGQFTEASRAYCAQVIARLAEQGAQGVIFGCTEIGLLVPEERSVLPVFDTAAIHAEDA
83 -> 85 TNT

 

Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0005515 - protein binding
GO:0016853 - isomerase activity
GO:0016855 - racemase and epimerase activity, acting on amino acids and derivatives
GO:0047661 - amino-acid racemase activity
GO:0036361 - racemase activity, acting on amino acids and derivatives
biological_process GO:0006807 - nitrogen compound metabolic process
External database links:  
DIP:
DIP-12147N
ECOCYC:
EG11157-MONOMER
ECOLIWIKI:
b2840
INTERPRO:
IPR001920
INTERPRO:
IPR033134
INTERPRO:
IPR018187
INTERPRO:
IPR004380
INTERPRO:
IPR015942
MODBASE:
P03813
PANTHER:
PTHR21198:SF7
PFAM:
PF01177
PRIDE:
P03813
PROSITE:
PS00923
PROSITE:
PS00924
REFSEQ:
NP_417317
SMR:
P03813
UNIPROT:
P03813


Operon      
Name: araE-ygeA         
Operon arrangement:
Transcription unit        Promoter
araE
araE-ygeA
 


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, AraC


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3140 2978995 forward nd [RS-EPT-CBR] [1]
  promoter ygeAp5 2980803 reverse Similarity to the consensus
Read more >
[ICWHO] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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