RegulonDB RegulonDB 10.8: Gene Form
   

dinD gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yicC dinD yicG ligB LexA terminator anti-terminator TSS_4220 TSS_4220 dinDp dinDp

Gene      
Name: dinD    Texpresso search in the literature
Synonym(s): ECK3635, EG11193, b3645, pcsA, yicD
Genome position(nucleotides): 3817760 --> 3818584 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
45.82
External database links:  
ASAP:
ABE-0011918
CGSC:
33582
ECHOBASE:
EB1179
OU-MICROARRAY:
b3645
PortEco:
dinD
STRING:
511145.b3645
COLOMBOS: dinD


Product      
Name: DNA damage-inducible protein D
Synonym(s): DinD, PcsA, YicD
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 31.078
Isoelectric point: 8.639
Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.1 - DNA related --> 2.1.4 - DNA repair
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
biological_process GO:0006974 - cellular response to DNA damage stimulus
GO:0009432 - SOS response
Note(s): Note(s): ...[more].
Evidence: [IEP] Inferred from expression pattern
[IGI] Inferred from genetic interaction
[IMP] Inferred from mutant phenotype
Reference(s): [1] Bagg A., et al., 1981
[2] Bernstein C., et al., 1999
[3] Kenyon CJ., et al., 1982
[4] Kenyon CJ., et al., 1980
[5] Ohmori H., et al., 1995
[6] Yasuda T., et al., 1996
[7] Zheng M., et al., 2001
External database links:  
ECOCYC:
EG11193-MONOMER
ECOLIWIKI:
b3645
PRIDE:
P23840
PRODB:
PRO_000022447
REFSEQ:
NP_418102
UNIPROT:
P23840


Operon      
Name: dinD         
Operon arrangement:
Transcription unit        Promoter
dinD


Transcriptional Regulation      
Display Regulation             
Repressed by: LexA
Growth Conditions:

[1] 

C: Escherichia coli| protox assay
E: Escherichia coli| chenodeoxycholate; protox assay

[2] 

C: Escherichia coli| protox assay
E: Escherichia coli| protox assay; ursodeoxycholate

[3] 

C: Escherichia coli| protox assay
E: Escherichia coli| glycocholate; protox assay

[4] 

C: Escherichia coli| protox assay
E: Escherichia coli| deoxycholate; protox assay



Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4220 3817701 forward nd [RS-EPT-CBR] [8]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Bagg A., Kenyon CJ., Walker GC., 1981, Inducibility of a gene product required for UV and chemical mutagenesis in Escherichia coli., Proc Natl Acad Sci U S A 78(9):5749-53

 [2] Bernstein C., Bernstein H., Payne CM., Beard SE., Schneider J., 1999, Bile salt activation of stress response promoters in Escherichia coli., Curr Microbiol 39(2):68-72

 [3] Kenyon CJ., Brent R., Ptashne M., Walker GC., 1982, Regulation of damage-inducible genes in Escherichia coli., J Mol Biol 160(3):445-57

 [4] Kenyon CJ., Walker GC., 1980, DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli., Proc Natl Acad Sci U S A 77(5):2819-23

 [5] Ohmori H., Saito M., Yasuda T., Nagata T., Fujii T., Wachi M., Nagai K., 1995, The pcsA gene is identical to dinD in Escherichia coli., J Bacteriol 177(1):156-65

 [6] Yasuda T., Nagata T., Ohmori H., 1996, Multicopy suppressors of the cold-sensitive phenotype of the pcsA68 (dinD68) mutation in Escherichia coli., J Bacteriol 178(13):3854-9

 [7] Zheng M., Wang X., Templeton LJ., Smulski DR., LaRossa RA., Storz G., 2001, DNA microarray-mediated transcriptional profiling of the Escherichia coli response to hydrogen peroxide., J Bacteriol 183(15):4562-70

 [8] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


RegulonDB