RegulonDB

RegulonDB RegulonDB 10.8: Gene Form

rstB gene in Escherichia coli K-12 genome

Gene local context to scale (view description)

Gene
Name:	rstB
Synonym(s):	ECK1604, EG11233, b1609, uspT
Genome position(nucleotides):	1682882 --> 1684183 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	50.69
External database links:

ASAP:	ABE-0005372
ECHOBASE:	EB1215
OU-MICROARRAY:	b1609
PortEco:	rstB
STRING:	511145.b1609
COLOMBOS:	rstB

Product

Name:

sensory histidine kinase RstB

Synonym(s):

RstB, UspT

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

49.283

Isoelectric point:

6.198

Motif(s):

Type	Positions	Sequence
	166 -> 206	KLEAAAQRFGDGHLNERIHFDEGSSFERLGVAFNQMADNIN
	320 -> 423	MERVLDNLLNNALRYCHSTVETSLLLSGNRATLIVEDDGPGIAPENREHIFEPFVRLDPSRDRSTGGCGLGLAIVHSIALAMGGTVNCDTSELGGARFSFSWPL
	218 -> 425	GIAHELRTPLVRLRYRLEMSDNLSAAESQALNRDISQLEALIEELLTYARLDRPQNELHLSEPDLPLWLSTHLADIQAVTPDKTVRIKTLVQGHYAALDMRLMERVLDNLLNNALRYCHSTVETSLLLSGNRATLIVEDDGPGIAPENREHIFEPFVRLDPSRDRSTGGCGLGLAIVHSIALAMGGTVNCDTSELGGARFSFSWPLWH
	211 -> 269	SKKQLIDGIAHELRTPLVRLRYRLEMSDNLSAAESQALNRDISQLEALIEELLTYARLD
	4 -> 24	LFIQFYLLLFVCFLVMSLLVG

Classification:

Multifun Terms (GenProtEC)
		2 - information transfer --> 2.3 - protein related --> 2.3.3 - posttranslational modification
		3 - regulation --> 3.1 - type of regulation --> 3.1.2 - transcriptional level --> 3.1.2.4 - complex regulation --> 3.1.2.4.3 - two component regulatory systems (external signal)
		3 - regulation --> 3.1 - type of regulation --> 3.1.3 - posttranscriptional --> 3.1.3.2 - covalent modification, demodification, maturation
		6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0005887 - integral component of plasma membrane GO:0016021 - integral component of membrane
	molecular_function	GO:0016740 - transferase activity GO:0016772 - transferase activity, transferring phosphorus-containing groups GO:0016301 - kinase activity GO:0000166 - nucleotide binding GO:0005524 - ATP binding GO:0000155 - phosphorelay sensor kinase activity GO:0004673 - protein histidine kinase activity
	biological_process	GO:0016310 - phosphorylation GO:0047484 - regulation of response to osmotic stress GO:0000160 - phosphorelay signal transduction system GO:0007165 - signal transduction GO:0046777 - protein autophosphorylation GO:0018106 - peptidyl-histidine phosphorylation GO:0023014 - signal transduction by protein phosphorylation

Note(s):

Note(s): ...[more].

Evidence:

[APPH] Assay of protein purified to homogeneity

Reference(s):

[1] Yamamoto K., et al., 2005

External database links:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

MODBASE:

PFAM:

PFAM:

PFAM:

PRIDE:

PRINTS:

PRODB:

PROSITE:

PROSITE:

REFSEQ:

SMART:

SMART:

SMART:

SMR:

SWISSMODEL:

UNIPROT:

Operon

Name:

rstAB

Operon arrangement:

Transcription unit	Promoter
rstAB	rstAp

Transcriptional Regulation
	Display Regulation
Activated by:	PhoP

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	tusp2	1684173		forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: poor homology. Score: 0.96. P-value: 2.991e-6 Read more >	[ICWHO]	[2]

Evidence
[ICWHO] Inferred computationally without human oversight

Reference(s)
[1] Yamamoto K., Hirao K., Oshima T., Aiba H., Utsumi R., Ishihama A., 2005, Functional characterization in vitro of all two-component signal transduction systems from Escherichia coli., J Biol Chem 280(2):1448-56
[2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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