RegulonDB RegulonDB 10.8: Gene Form
   

argE gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ppc argE argC ArgR ArgR Cra argEp2 argEp2 argEp1 argEp1 TSS_4685 TSS_4685 argCp argCp TSS_4684 (cluster) TSS_4684 (cluster) TSS_4683 TSS_4683 TSS_4682 TSS_4682 TSS_4681 TSS_4681 TSS_4680 TSS_4680 ppcp ppcp TSS_4679 (cluster) TSS_4679 (cluster) TSS_4678 TSS_4678 TSS_4677 TSS_4677 TSS_4676 (cluster) TSS_4676 (cluster) TSS_4675 TSS_4675 TSS_4674 TSS_4674 TSS_4673 TSS_4673 TSS_4672 TSS_4672 TSS_4671 TSS_4671 TSS_4670 TSS_4670 TSS_4669 TSS_4669 TSS_4668 TSS_4668 TSS_4667 TSS_4667 TSS_4666 TSS_4666 TSS_4665 TSS_4665 TSS_4664 (cluster) TSS_4664 (cluster) TSS_4663 (cluster) TSS_4663 (cluster) TSS_4662 TSS_4662 TSS_4661 TSS_4661 TSS_4660 TSS_4660 TSS_4659 TSS_4659 TSS_4658 TSS_4658 TSS_4657 TSS_4657 TSS_4656 TSS_4656 TSS_4655 (cluster) TSS_4655 (cluster) TSS_4654 TSS_4654

Gene      
Name: argE    Texpresso search in the literature
Synonym(s): ECK3948, EG11286, b3957
Genome position(nucleotides): 4153696 <-- 4154847 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 51.74
External database links:  
ASAP:
 ABE-0012955
CGSC:
 1017
ECHOBASE:
 EB1263
NCBI-GENE:
 948456
OU-MICROARRAY:
 b3957
PortEco:
 argE
STRING:
 511145.b3957
COLOMBOS: argE


Product      
Name: acetylornithine deacetylase
Synonym(s): ArgE
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 42.347
Isoelectric point: 5.792
Motif(s):
 
Type Positions Sequence
178 -> 288 AHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSER
76 -> 377 LLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFAETTALRPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVI

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.3 - arginine
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0016787 - hydrolase activity
GO:0046872 - metal ion binding
GO:0008270 - zinc ion binding
GO:0008237 - metallopeptidase activity
GO:0008777 - acetylornithine deacetylase activity
GO:0042803 - protein homodimerization activity
GO:0050897 - cobalt ion binding
biological_process GO:0006508 - proteolysis
GO:0006526 - arginine biosynthetic process
GO:0008652 - cellular amino acid biosynthetic process
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
 ACETYLORNDEACET-MONOMER
ECOLIWIKI:
 b3957
INTERPRO:
 IPR001261
INTERPRO:
 IPR036264
INTERPRO:
 IPR011650
INTERPRO:
 IPR010169
INTERPRO:
 IPR002933
MODBASE:
 P23908
PANTHER:
 PTHR43808:SF1
PFAM:
 PF01546
PFAM:
 PF07687
PRIDE:
 P23908
PRODB:
 PRO_000022129
PROSITE:
 PS00758
PROSITE:
 PS00759
REFSEQ:
 NP_418392
SMR:
 P23908
SWISSMODEL:
 P23908
UNIPROT:
 P23908


Operon      
Name: argE         
Operon arrangement:
Transcription unit        Promoter
argE
argE


Transcriptional Regulation      
Display Regulation             
Repressed by: ArgR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4654 4151068 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4655 (cluster) 4151679 reverse For this promoter, there
Read more > 		[RS-EPT-CBR] [1]
  promoter TSS_4656 4151684 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4657 4151686 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4658 4151694 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4659 4151698 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4660 4151717 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4661 4151894 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4662 4151903 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4663 (cluster) 4151918 reverse For this promoter, there
Read more > 		[RS-EPT-CBR] [1]
  promoter TSS_4664 (cluster) 4151922 reverse For this promoter, there
Read more > 		[RS-EPT-CBR] [1]
  promoter TSS_4665 4152046 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4666 4152049 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4667 4152053 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4668 4152060 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4669 4152085 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4670 4152149 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4671 4152153 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4672 4152158 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4673 4152164 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4674 4152443 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4675 4152528 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4676 (cluster) 4152676 reverse For this promoter, there
Read more > 		[RS-EPT-CBR] [1]
  promoter TSS_4677 4152914 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4678 4153121 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4679 (cluster) 4153188 reverse For this promoter, there
Read more > 		[RS-EPT-CBR] [1]
  promoter TSS_4680 4153572 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4681 4153575 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4682 4153694 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4683 4153697 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4684 (cluster) 4154883 forward For this promoter, there
Read more > 		[RS-EPT-CBR] [1]
  promoter TSS_4685 4154887 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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