RegulonDB 8.2: Gene Form

Gene
Name:	gadB
Synonym(s):	b1493
Genome position(nucleotides):	1568669 <-- 1570069 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	53.32
External database links:

ECOCYC:	EG11490
GENBANK:	1787769
GENBANK_RefSeq:	16129452
OU-MICROARRAY:	b1493
M3D:	gadB
PortEco:	b1493

Product

Name:

glutamate decarboxylase B subunit

Synonym(s):

GadB

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol,membrane

Molecular weight:

52.668

Isoelectric point:

5.14

Motif(s):

Classification:

cell processes --> adaptations --> pH

Note(s):

Note(s): ...[more].

Reference(s):

External database links:

ECOCYC:

EXPASY:

GENPROTEC:

GO:

PDB:

Operon

Name:

gadBC

Operon arrangement:

Transcriptional Regulation
	Display Regulation
	Note: The TF binding sites with unknown position are not displayed in the graphic.
Activated by:	GadX, GadW, AdiY, RcsB, GadE
Repressed by:	FliZ, CRP, GadW, Fis

Regulation by small RNA
	Display Regulation
small RNA	oxyS

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	TSS_1671	1569644		reverse	nd	[RS-EPT-CBR]	[4]
	promoter	TSS_1672	1570097		reverse	nd	[RS-EPT-CBR]	[4]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] De Biase D., Tramonti A., Bossa F., Visca P., 1999, The response to stationary-phase stress conditions in Escherichia coli: role and regulation of the glutamic acid decarboxylase system., Mol Microbiol. 32(6):1198-211
[2] Lin J., Lee IS., Frey J., Slonczewski JL., Foster JW., 1995, Comparative analysis of extreme acid survival in Salmonella typhimurium, Shigella flexneri, and Escherichia coli., J Bacteriol. 177(14):4097-104
[3] Smith DK., Kassam T., Singh B., Elliott JF., 1992, Escherichia coli has two homologous glutamate decarboxylase genes that map to distinct loci., J Bacteriol. 174(18):5820-6
[4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Mu¿¿iz-Rascado L, Garc¿¿a-Sotelo JS, Weiss V, Solano-Lira H, Mart¿¿nez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hern¿¿ndez S, Alquicira-Hern¿¿ndez K, L¿¿pez-Fuentes A, Porr¿¿n-Sotelo L, Huerta AM, Bonavides-Mart¿¿nez C, Balderas-Mart¿¿nez YI, Pannier L, Olvera M, Labastida A, Jim¿¿nez-Jacinto V, Vega-Alvarado L, Del Moral-Ch¿¿vez V, Hern¿¿ndez-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.