RegulonDB RegulonDB 10.8: Gene Form
   

mltG gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

mltG holB pabC tmk TSS_1420 TSS_1420 TSS_1419 TSS_1419 TSS_1418 TSS_1418

Gene      
Name: mltG    Texpresso search in the literature
Synonym(s): ECK1083, EG11494, b1097, yceG
Genome position(nucleotides): 1154112 --> 1155134 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
50.73
External database links:  
ASAP:
ABE-0003712
ECHOBASE:
EB1457
OU-MICROARRAY:
b1097
PortEco:
yceG
STRING:
511145.b1097
COLOMBOS: mltG


Product      
Name: endolytic murein transglycosylase
Synonym(s): MltG, YceG
Sequence: Get amino acid sequence Fasta Format
Cellular location: periplasmic space,inner membrane
Molecular weight: 38.247
Isoelectric point: 9.926
Motif(s):
 
Type Positions Sequence
1 -> 4 MKKV
5 -> 24 LLIILLLLVVLGIAAGVGVW
25 -> 340 KVRHLADSKLLIKEETIFTLKPGTGRLALGEQLYADKIINRPRVFQWLLRIEPDLSHFKAGTYRFTPQMTVREMLKLLESGKEAQFPLRLVEGMRLSDYLKQLREAPYIKHTLSDDKYATVAQALELENPEWIEGWFWPDTWMYTANTTDVALLKRAHKKMVKAVDSAWEGRADGLPYKDKNQLVTMASIIEKETAVASERDKVASVFINRLRIGMRLQTDPTVIYGMGERYNGKLSRADLETPTAYNTYTITGLPPGAIATPGADSLKAAAHPAKTPYLYFVADGKGGHTFNTNLASHNKSVQDYLKVLKEKNAQ
4 -> 24 VLLIILLLLVVLGIAAGVGVW
218 -> 218 E

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.7 - murein (peptidoglycan)
  5 - cell processes --> 5.1 - cell division
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0005515 - protein binding
GO:0016829 - lyase activity
GO:0008933 - lytic transglycosylase activity
GO:0042802 - identical protein binding
GO:0008932 - lytic endotransglycosylase activity
biological_process GO:0000270 - peptidoglycan metabolic process
GO:0000910 - cytokinesis
GO:0009252 - peptidoglycan biosynthetic process
GO:0071555 - cell wall organization
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
EG11494-MONOMER
ECOLIWIKI:
b1097
INTERPRO:
IPR003770
PANTHER:
PTHR30518
PDB:
2R1F
PFAM:
PF02618
PRIDE:
P28306
REFSEQ:
NP_415615
SMR:
P28306
UNIPROT:
P28306


Operon      
Name: pabC-mltG-tmk-holB-ycfH         
Operon arrangement:
Transcription unit        Promoter
 


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1418 1155058 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1419 1156471 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1420 1156478 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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