RegulonDB RegulonDB 10.6.3: Gene Form
   

caiT gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

caiT caiA fixA CaiF CRP CaiF CaiF CRP CaiF ArcA ArcA FNR FNR CRP ArcA ArcA fixAp fixAp caiTp caiTp

Gene      
Name: caiT    Texpresso search in the literature
Synonym(s): ECK0041, EG11561, b0040, yaaP
Genome position(nucleotides): 40417 <-- 41931 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
51.82
External database links:  
ASAP:
ABE-0000141
CGSC:
36822
ECHOBASE:
EB1522
ECOCYC:
EG11561
ECOLIHUB:
caiT
OU-MICROARRAY:
b0040
REGULONDB:
b0040
STRING:
511145.b0040
M3D: caiT
COLOMBOS: caiT
PortEco: b0040


Product      
Name: L-carnitine:γ-butyrobetaine antiporter
Synonym(s): CaiT, YaaP
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 56.587
Isoelectric point: 8.317
Motif(s):
 
Type Positions Sequence
92 -> 112 IFMMFASCTSAAVLFWGSIEI
143 -> 163 GPLPWATYSFLSVAFAYFFFV
353 -> 353 L
14 -> 500 VFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQ
316 -> 336 WTVFYWAWWVIYAIQMSIFLA

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015297 - antiporter activity
GO:0022857 - transmembrane transporter activity
GO:0015226 - carnitine transmembrane transporter activity
GO:0044667 - (R)-carnitine:4-(trimethylammonio)butanoate antiporter activity
biological_process GO:0009437 - carnitine metabolic process
GO:0055085 - transmembrane transport
GO:0015879 - carnitine transport
GO:0071705 - nitrogen compound transport
GO:1900749 - (R)-carnitine transport
GO:1900751 - 4-(trimethylammonio)butanoate transport
GO:1902270 - (R)-carnitine transmembrane transport
GO:1902603 - carnitine transmembrane transport
External database links:  
DIP:
DIP-9247N
ECOCYC:
CAIT-MONOMER
ECOLIWIKI:
b0040
INTERPRO:
IPR023449
INTERPRO:
IPR000060
INTERPRO:
IPR018093
PANTHER:
PTHR30047
PDB:
2WSX
PDB:
3HFX
PFAM:
PF02028
PRIDE:
P31553
PRODB:
PRO_000022246
PROSITE:
PS01303
PROTEINMODELPORTAL:
P31553
REFSEQ:
NP_414582
SMR:
P31553
UNIPROT:
P31553


Operon      
Name: caiTABCDE         
Operon arrangement:
Transcription unit        Promoter
caiTABCDE
caiCDE


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, FNR, ArcA, CaiF
Repressed by: H-NS


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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