RegulonDB

Gene
Name:	fixB
Synonym(s):	ECK0043, EG11563, b0042, yaaR
Genome position(nucleotides):	43188 --> 44129
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	56.69
External database links:

ASAP:	ABE-0000147
ECHOBASE:	EB1524
ECOLIHUB:	fixB
MIM:	231680
OU-MICROARRAY:	b0042
STRING:	511145.b0042
COLOMBOS:	fixB

Product

Name:

putative electron transfer flavoprotein FixB

Synonym(s):

FixB, YaaR, putative electron transfer flavoprotein, NAD/FAD-binding domain and ETFP adenine nucleotide-binding domain-like

Sequence:

Get amino acid sequence Fasta Format

Molecular weight:

33.513

Isoelectric point:

7.146

Motif(s):

Type	Positions	Sequence	Comment
	42 -> 169	AQAIQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDASRTGETHTVE
	191 -> 271	DLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGA
	255 -> 283	LYLAVGISGQIQHMVGANASQTIFAINKD	UniProt: FAD.

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		1 - metabolism --> 1.4 - energy production/transport
Gene Ontology Terms (GO)
	molecular_function	GO:0005515 - protein binding GO:0009055 - electron transfer activity GO:0050660 - flavin adenine dinucleotide binding
	biological_process	GO:0009437 - carnitine metabolic process GO:0042413 - carnitine catabolic process GO:0022900 - electron transport chain GO:0033539 - fatty acid beta-oxidation using acyl-CoA dehydrogenase

Note(s):

Note(s): ...[more].

Evidence:

[COMP-HINF-FN-FROM-SEQ] Human inference of function from sequence
[EXP-IMP] Inferred from mutant phenotype

Reference(s):

[1] Eichler K., et al., 1995
[2] Walt A., et al., 2002

External database links:

ALPHAFOLD:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

MODBASE:

PFAM:

PFAM:

PRIDE:

PRODB:

PROSITE:

REFSEQ:

SMART:

SMR:

UNIPROT:

Operon

Name:

fixABCX

Operon arrangement:

Transcription unit	Promoter
fixABCX	fixAp

Transcriptional Regulation
	Display Regulation
Activated by:	CRP, FNR, CaiF

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References

Reference(s)
[1] Eichler K., Buchet A., Bourgis F., Kleber HP., Mandrand-Berthelot MA., 1995, The fix Escherichia coli region contains four genes related to carnitine metabolism., J Basic Microbiol 35(4):217-27
[2] Walt A., Kahn ML., 2002, The fixA and fixB genes are necessary for anaerobic carnitine reduction in Escherichia coli., J Bacteriol 184(14):4044-7