RegulonDB RegulonDB 10.7: Gene Form
   

yaaU gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yaaU kefF fixX kefC fixC TSS_82 TSS_82 kefFp2 kefFp2 yaaUp yaaUp

Gene      
Name: yaaU    Texpresso search in the literature
Synonym(s): ECK0046, EG11566, b0045, yabE
Genome position(nucleotides): 45807 --> 47138 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
53.3
External database links:  
ASAP:
ABE-0000156
ECHOBASE:
EB1527
OU-MICROARRAY:
b0045
PORTECO:
yaaU
REGULONDB:
b0045
STRING:
511145.b0045
M3D: yaaU
COLOMBOS: yaaU
PortEco: b0045


Product      
Name: putative transporter YaaU
Synonym(s): YaaU, YabE
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 48.667
Isoelectric point: 8.682
Motif(s):
 
Type Positions Sequence
146 -> 166 FIAAMWYVGATCADLVGYWLY
374 -> 394 VIMSLSRIGTIVSTWALPIFI
19 -> 39 ILLWGSGGPFLDGYVLVMIGV
114 -> 134 VLIGIVIGADYPIATSMITEF
242 -> 262 FPFVLFVAAIWTCQVIPMFAI

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0022857 - transmembrane transporter activity
biological_process GO:0006979 - response to oxidative stress
GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Evidence: [HIFS] Human inference of function from sequence
Reference(s): [1] Jindal S., et al., 2019
[2] Pao SS., et al., 1998
External database links:  
ECOCYC:
YAAU-MONOMER
ECOLIWIKI:
b0045
INTERPRO:
IPR020846
INTERPRO:
IPR005828
INTERPRO:
IPR036259
MODBASE:
P31679
PFAM:
PF00083
PRIDE:
P31679
PROSITE:
PS50850
PROTEINMODELPORTAL:
P31679
REFSEQ:
NP_414587
SMR:
P31679
UNIPROT:
P31679


Operon      
Name: yaaU         
Operon arrangement:
Transcription unit        Promoter
 


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter kefFp2 47080 forward Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter TSS_82 47215 forward nd [RS-EPT-CBR] [4]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

 [2] Pao SS., Paulsen IT., Saier MH., 1998, Major facilitator superfamily., Microbiol Mol Biol Rev 62(1):1-34

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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