RegulonDB RegulonDB 10.7: Gene Form
   

kefF gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

kefC yaaU kefF folA IHF TyrR TyrR folAp folAp TSS_82 TSS_82 kefFp2 kefFp2

Gene      
Name: kefF    Texpresso search in the literature
Synonym(s): ECK0047, EG11568, b0046, yabF
Genome position(nucleotides): 47246 --> 47776 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
54.61
External database links:  
ASAP:
ABE-0000159
ECHOBASE:
EB1528
OU-MICROARRAY:
b0046
PORTECO:
kefF
REGULONDB:
b0046
STRING:
511145.b0046
M3D: kefF
COLOMBOS: kefF
PortEco: b0046


Product      
Name: regulator of KefC-mediated potassium transport and quinone oxidoreductase
Synonym(s): KefF, YabF
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol,inner membrane
Molecular weight: 20.17
Isoelectric point: 6.561
Motif(s):
 
Type Positions Sequence
65 -> 68 MQWY
149 -> 149 F
41 -> 41 D
105 -> 108 TTGG
112 -> 112 H

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism
  3 - regulation --> 3.1 - type of regulation --> 3.1.3 - posttranscriptional --> 3.1.3.3 - inhibition / activation of enzymes
  4 - transport
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0016020 - membrane
GO:0005886 - plasma membrane
molecular_function GO:0009055 - electron transfer activity
GO:0016491 - oxidoreductase activity
GO:0003955 - NAD(P)H dehydrogenase (quinone) activity
GO:0010181 - FMN binding
GO:0042803 - protein homodimerization activity
biological_process GO:0006813 - potassium ion transport
GO:0022900 - electron transport chain
GO:0055114 - oxidation-reduction process
GO:0032414 - positive regulation of ion transmembrane transporter activity
GO:1901381 - positive regulation of potassium ion transmembrane transport
External database links:  
DIP:
DIP-35822N
ECOCYC:
EG11568-MONOMER
ECOLIWIKI:
b0046
INTERPRO:
IPR029039
INTERPRO:
IPR023948
INTERPRO:
IPR003680
MODBASE:
P0A754
PANTHER:
PTHR47307:SF2
PDB:
3L9X
PDB:
3L9W
PDB:
3EYW
PFAM:
PF02525
PRIDE:
P0A754
PRODB:
PRO_000023063
PROTEINMODELPORTAL:
P0A754
REFSEQ:
NP_414588
SMR:
P0A754
UNIPROT:
P0A754


Operon      
Name: kefFC         
Operon arrangement:
Transcription unit        Promoter
 


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter kefFp2 47080 forward Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter TSS_82 47215 forward nd [RS-EPT-CBR] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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