RegulonDB RegulonDB 10.8: Gene Form
   

tehB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

tehA ydcK ydcL tehB rimL NsrR NsrR terminator anti-terminator anti-anti-terminator terminator ydcLp5 ydcLp5 ydcLp6 ydcLp6 ydcLp1 ydcLp1 ydcLp4 ydcLp4 ydcLp7 ydcLp7 TSS_1811 TSS_1811 TSS_1810 TSS_1810 TSS_1809 TSS_1809 ydcKp8 ydcKp8 tehAp tehAp

Gene      
Name: tehB    Texpresso search in the literature
Synonym(s): ECK1423, EG11884, b1430
Genome position(nucleotides): 1501562 --> 1502155 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
45.96
External database links:  
ASAP:
ABE-0004772
CGSC:
32109
ECHOBASE:
EB1830
OU-MICROARRAY:
b1430
PortEco:
tehB
STRING:
511145.b1430
COLOMBOS: tehB


Product      
Name: tellurite methyltransferase
Synonym(s): TehB
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 22.531
Isoelectric point: 7.424
Motif(s):
 
Type Positions Sequence
176 -> 176 H
86 -> 87 DL
97 -> 97 D
98 -> 98 F
177 -> 177 R

 

Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes --> 5.6 - protection --> 5.6.4 - drug resistance/sensitivity
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0008168 - methyltransferase activity
GO:0016740 - transferase activity
GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity
biological_process GO:0009636 - response to toxic substance
GO:0046677 - response to antibiotic
GO:0032259 - methylation
GO:0046690 - response to tellurium ion
External database links:  
DIP:
DIP-10978N
ECOCYC:
EG11884-MONOMER
ECOLIWIKI:
b1430
INTERPRO:
IPR004537
INTERPRO:
IPR029063
INTERPRO:
IPR015985
MINT:
MINT-1274665
MODBASE:
P25397
PANTHER:
PTHR10108:SF1022
PDB:
2XVA
PDB:
2XVM
PFAM:
PF03848
PRIDE:
P25397
PRODB:
PRO_000024047
REFSEQ:
NP_415947
SMR:
P25397
UNIPROT:
P25397


Operon      
Name: tehAB         
Operon arrangement:
Transcription unit        Promoter
tehAB


Transcriptional Regulation      
Display Regulation             
Repressed by: NsrR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter ydcKp8 1500640 reverse Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter TSS_1809 1501349 forward nd [RS-EPT-CBR] [2]
  promoter TSS_1810 1501486 forward nd [RS-EPT-CBR] [2]
  promoter TSS_1811 1501538 forward nd [RS-EPT-CBR] [2]
  promoter ydcLp7 1502323 forward Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter ydcLp4 1502345 forward Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter ydcLp1 1502369 forward Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter ydcLp6 1502445 forward Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter ydcLp5 1502446 forward Similarity to the consensus
Read more >
[ICWHO] [1]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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