RegulonDB RegulonDB 10.8: Gene Form
   

plaP gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

plaP yeeE yeeY yoeI anti-anti-terminator anti-terminator terminator terminator yeeFp2 yeeFp2 yeeEp yeeEp TSS_2321 TSS_2321 TSS_2320 TSS_2320

Gene      
Name: plaP    Texpresso search in the literature
Synonym(s): ECK2008, EG11896, b2014, yeeF
Genome position(nucleotides): 2085704 <-- 2087062 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 52.69
External database links:  
ASAP:
 ABE-0006696
ECHOBASE:
 EB1842
OU-MICROARRAY:
 b2014
PortEco:
 yeeF
STRING:
 511145.b2014
COLOMBOS: plaP


Product      
Name: putrescine:H+ symporter PlaP
Synonym(s): PlaP, YeeF
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 49.538
Isoelectric point: 8.902
Motif(s):
 
Type Positions Sequence
57 -> 409 FALIAILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSSLLDYLFAPMINILLAKIYFEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIVVLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFDGISNLSEETKDAERVIPRAIFLTALIGGMIFIFATYFLQLYFPDISRFKDPDASQPEIMLYVAGKAFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWRTPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLKDHFQYLFLPMCGALTVG
124 -> 144 LVPSIPSWMFVVALVAFMTAF
238 -> 258 IFLTALIGGMIFIFATYFLQL
395 -> 415 FQYLFLPMCGALTVGALWVNL
418 -> 438 SSMVLGLIWAAIGLIYLACVT

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015295 - solute:proton symporter activity
GO:0015489 - putrescine transmembrane transporter activity
GO:0022857 - transmembrane transporter activity
biological_process GO:0006865 - amino acid transport
GO:0055085 - transmembrane transport
GO:0048870 - cell motility
GO:0015847 - putrescine transport
GO:1902600 - proton transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
 YEEF-MONOMER
ECOLIWIKI:
 b2014
INTERPRO:
 IPR002293
PANTHER:
 PTHR11785
PFAM:
 PF13520
PRIDE:
 P0AA47
PROSITE:
 PS00218
REFSEQ:
 NP_416518
SMR:
 P0AA47
UNIPROT:
 P0AA47


Operon      
Name: plaP         
Operon arrangement:
Transcription unit        Promoter
 


RNA cis-regulatory element    
Attenuation: Translational


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2320 2084549 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2321 2085498 reverse nd [RS-EPT-CBR] [1]
  promoter yeeFp2 2087238 reverse Similarity to the consensus
Read more > 		[ICWHO] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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