RegulonDB RegulonDB 10.6.3: Gene Form
   

lldP gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

lldP lldD lldR yibL LldR ArcA ArcA LldR lldPp lldPp

Gene      
Name: lldP    Texpresso search in the literature
Synonym(s): ECK3593, EG11961, b3603, lct, lctP
Genome position(nucleotides): 3777399 --> 3779054 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
55.13
Reference(s): [1] Erwin AL., et al., 1996
External database links:  
ASAP:
ABE-0011777
CGSC:
35161
ECHOBASE:
EB1904
ECOCYC:
EG11961
ECOLIHUB:
lldP
ECOO157CYC:
LLDP
OU-MICROARRAY:
b3603
REGULONDB:
b3603
STRING:
511145.b3603
M3D: lldP
COLOMBOS: lldP
PortEco: b3603


Shine dalgarno      
Sequence: cgtggactccAGGAGAcctgcaATG


Product      
Name: lactate/glycolate:H+ symporter LldP
Synonym(s): Lct, LctP, LldP
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 59.168
Isoelectric point: 9.019
Motif(s):
 
Type Positions Sequence
37 -> 57 LKGYVAASWTVAIALAVALLF
16 -> 542 LSSLIASLPILFFFFALIKLKLKGYVAASWTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAWIIIAAVFVYKISVKTGQFDIIRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLCLIVNTAPVAFGAMGIPILVAGQVTGIDSFEIGQMVGRQLPFMTIIVLFWIMAIMDGWRGIKETWPAVVVAGGSFAIAQYLSSNFIGPELPDIISSLVSLLCLTLFLKRWQPVRVFRFGDLGASQVDMTLAHTGYTAGQVLRAWTPFLFLTATVTLWSIPPFKALFASGGALYEWVINIPVPYLDKLVARMPPVVSEATAYAAVFKFDWFSATGTAILFAALLSIVWLKMKPSDAISTFGSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLGWLGVFLTGSDTSSNALFAALQATAAQQIGVSDLLLVAANTTGGVTGKMISPQSIAIACAAVGLVGKESDLFRFTVKHSLIFTCIVGVITTLQ
159 -> 179 LCLIVNTAPVAFGAMGIPILV
13 -> 33 NIWLSSLIASLPILFFFFALI
70 -> 90 VYGFFYGLWPIAWIIIAAVFV

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015295 - solute:proton symporter activity
GO:0015129 - lactate transmembrane transporter activity
GO:0043879 - glycolate transmembrane transporter activity
biological_process GO:0006974 - cellular response to DNA damage stimulus
GO:0015727 - lactate transport
GO:0035873 - lactate transmembrane transport
GO:1902600 - proton transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-10109N
ECOCYC:
LCTP-MONOMER
ECOLIWIKI:
b3603
INTERPRO:
IPR003804
MINT:
MINT-1233464
PANTHER:
PTHR30003
PFAM:
PF02652
PRIDE:
P33231
PRODB:
PRO_000023101
PROTEINMODELPORTAL:
P33231
REFSEQ:
NP_418060
SMR:
P33231
UNIPROT:
P33231


Operon      
Name: lldPRD         
Operon arrangement:
Transcription unit        Promoter
lldPRD


Transcriptional Regulation      
Display Regulation             
Activated by: LldR
Repressed by: LldR, ArcA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Erwin AL., Gotschlich EC., 1996, Cloning of a Neisseria meningitidis gene for L-lactate dehydrogenase (L-LDH): evidence for a second meningococcal L-LDH with different regulation., J Bacteriol 178(16):4807-13


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