RegulonDB

Gene
Name:	ftp
Synonym(s):	ECK2206, EG12073, apbE, b2214, yojK, yojL
Genome position(nucleotides):	2310479 <-- 2311534 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	53.41
External database links:

ASAP:	ABE-0007317
ECHOBASE:	EB1998
OU-MICROARRAY:	b2214
PortEco:	apbE
STRING:	511145.b2214
COLOMBOS:	ftp

Product

Name:

FAD:protein FMN transferase

Synonym(s):

ApbE, Ftp, YojK, YojL, flavin transferase

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane,periplasmic space

Molecular weight:

38.549

Isoelectric point:

5.436

Motif(s):

Type	Positions	Sequence
	42 -> 325	MGTFWRASIPGIDAKRSAELKEKIQTQLDADDQLLSTYKKDSALMRFNDSQSLSPWPVSEAMADIVTTSLRIGAKTDGAMDITVGPLVNLWGFGPEQQPVQIPSQEQIDAMKAKTGLQHLTVINQSHQQYLQKDLPDLYVDLSTVGEGYAADHLARLMEQEGISRYLVSVGGALNSRGMNGEGLPWRVAIQKPTDKENAVQAVVDINGHGISTSGSYRNYYELDGKRLSHVIDPQTGRPIEHNLVSVTVIAPTALEADAWDTGLMVLGPEKAKEVVRREGLAVY
	120 -> 122	AMD
	79 -> 79	Y
	1 -> 19	MEISFTRVALLAAALFFVG
	20 -> 351	CDQKPQPAKTHATEVTVLEGKTMGTFWRASIPGIDAKRSAELKEKIQTQLDADDQLLSTYKKDSALMRFNDSQSLSPWPVSEAMADIVTTSLRIGAKTDGAMDITVGPLVNLWGFGPEQQPVQIPSQEQIDAMKAKTGLQHLTVINQSHQQYLQKDLPDLYVDLSTVGEGYAADHLARLMEQEGISRYLVSVGGALNSRGMNGEGLPWRVAIQKPTDKENAVQAVVDINGHGISTSGSYRNYYELDGKRLSHVIDPQTGRPIEHNLVSVTVIAPTALEADAWDTGLMVLGPEKAKEVVRREGLAVYMITKEGDSFKTWMSPQFKSFLVSEKN

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.19 - incorporation of metal ions
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0030288 - outer membrane-bounded periplasmic space GO:0005886 - plasma membrane GO:0031237 - intrinsic component of periplasmic side of plasma membrane
	molecular_function	GO:0016740 - transferase activity GO:0046872 - metal ion binding GO:0071949 - FAD binding
	biological_process	GO:0017013 - protein flavinylation

Note(s):

Note(s): ...[more].

Evidence:

[APPH] Assay of protein purified to homogeneity

Reference(s):

[1] Chan YK., et al., 1997
[2] Deka RK., et al., 2016
[3] Gonnet P., et al., 2004
[4] Juncker AS., et al., 2003

External database links:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

PANTHER:

PDB:

PDB:

PDB:

PDB:

PFAM:

PRIDE:

PRODB:

PROSITE:

REFSEQ:

SMR:

UNIPROT:

Reference(s)
[1] Chan YK., McCormick WA., Watson RJ., 1997, A new nos gene downstream from nosDFY is essential for dissimilatory reduction of nitrous oxide by Rhizobium (Sinorhizobium) meliloti., Microbiology 143 ( Pt 8):2817-24
[2] Deka RK., Brautigam CA., Liu WZ., Tomchick DR., Norgard MV., 2016, Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm., Microbiologyopen 5(1):21-38
[3] Gonnet P., Rudd KE., Lisacek F., 2004, Fine-tuning the prediction of sequences cleaved by signal peptidase II: a curated set of proven and predicted lipoproteins of Escherichia coli K-12., Proteomics 4(6):1597-613
[4] Juncker AS., Willenbrock H., Von Heijne G., Brunak S., Nielsen H., Krogh A., 2003, Prediction of lipoprotein signal peptides in Gram-negative bacteria., Protein Sci 12(8):1652-62
[5] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

RNA cis-regulatory element

Attenuation:	Transcriptional