RegulonDB

Gene
Name:	feoA
Synonym(s):	ECK3395, EG12101, b3408
Genome position(nucleotides):	3540163 --> 3540390 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	48.68
External database links:

ASAP:	ABE-0011124
CGSC:	28964
ECHOBASE:	EB2025
ECOLIHUB:	feoA
OU-MICROARRAY:	b3408
STRING:	511145.b3408
COLOMBOS:	feoA

Product

Name:

ferrous iron transport protein A

Synonym(s):

FeoA

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol

Molecular weight:

8.371

Isoelectric point:

9.838

Motif(s):

Type	Positions	Sequence
	4 -> 71	TPDTAWKITGFSREISPAYRQKLLSLGMLPGSSFNVVRVAPLGDPIHIETRRVSLVLRKKDLALLEVE

Classification:

Multifun Terms (GenProtEC)
		4 - transport --> 4.9.A - Transporters of Unknown Classification
		5 - cell processes --> 5.5 - adaptations --> 5.5.7 - Fe aquisition
Gene Ontology Terms (GO)
	cellular_component	GO:0005737 - cytoplasm
	molecular_function	GO:0046914 - transition metal ion binding
	biological_process	GO:0006811 - ion transport GO:0006974 - cellular response to DNA damage stimulus GO:0055072 - iron ion homeostasis

Note(s):

Note(s): ...[more].

Evidence:

[IMP] Inferred from mutant phenotype

Reference(s):

[1] Kammler M., et al., 1993

External database links:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

PDB:

PFAM:

PRIDE:

PRODB:

REFSEQ:

SMART:

SMR:

UNIPROT:

Operon

Name:

feoABC

Operon arrangement:

Transcription unit	Promoter
feoABC	feoAp

Transcriptional Regulation
	Display Regulation
Activated by:	FNR, OmpR
Repressed by:	Fur
Undetermined regulation	NagC

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	TSS_4006	3540058	forward	nd	[RS-EPT-CBR]	[2]
promoter	TSS_4007	3540444	forward	nd	[RS-EPT-CBR]	[2]
promoter	TSS_4008 (cluster)	3540462	forward	nd	[RS-EPT-CBR]	[2]
promoter	TSS_4009	3540588	forward	nd	[RS-EPT-CBR]	[2]
promoter	TSS_4010	3542195	forward	nd	[RS-EPT-CBR]	[2]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Kammler M., Schon C., Hantke K., 1993, Characterization of the ferrous iron uptake system of Escherichia coli., J Bacteriol 175(19):6212-9
[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Reference(s)

[1] Kammler M., Schon C., Hantke K., 1993, Characterization of the ferrous iron uptake system of Escherichia coli., J Bacteriol 175(19):6212-9

[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.