RegulonDB

Gene
Name:	idnK
Synonym(s):	ECK4261, EG12152, b4268, gntV
Genome position(nucleotides):	4494623 --> 4495186 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	43.44
External database links:

ASAP:	ABE-0013980
CGSC:	17686
ECHOBASE:	EB2072
ECOLIHUB:	idnK
OU-MICROARRAY:	b4268
STRING:	511145.b4268
COLOMBOS:	idnK

Product

Name:

D-gluconate kinase, thermosensitive

Synonym(s):

GntV, IdnK, gluconokinase II

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol

Molecular weight:

21.004

Isoelectric point:

7.029

Motif(s):

Type	Positions	Sequence
	10 -> 17	GVSGSGKT
	12 -> 161	SGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPWLERLNDASYSLYKKNETGFIVCSSLKKQYRDILRKGSPHVHFLWLDGDYETILARMQRRAGHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTEQ

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
Gene Ontology Terms (GO)
	cellular_component	GO:0005829 - cytosol
	molecular_function	GO:0016740 - transferase activity GO:0016301 - kinase activity GO:0000166 - nucleotide binding GO:0005524 - ATP binding GO:0046316 - gluconokinase activity
	biological_process	GO:0005975 - carbohydrate metabolic process GO:0016310 - phosphorylation GO:0046183 - L-idonate catabolic process GO:0019521 - D-gluconate metabolic process GO:0046177 - D-gluconate catabolic process

Note(s):

Note(s): ...[more].

Reference(s):

[1] Gomez KM., et al., 2011
[2] Isturiz T., et al., 1997
[3] Wang IN., et al., 2001

External database links:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

MODBASE:

PFAM:

PRIDE:

PRODB:

REFSEQ:

SMR:

SWISSMODEL:

UNIPROT:

Operon

Name:

idnK

Operon arrangement:

Transcription unit	Promoter
idnK	idnKp

Transcriptional Regulation
	Display Regulation
Activated by:	CRP, IdnR
Repressed by:	GntR

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References

Reference(s)
[1] Gomez KM., Rodriguez A., Rodriguez Y., Ramirez AH., Isturiz T., 2011, The subsidiary GntII system for gluconate metabolism in Escherichia coli: alternative induction of the gntV gene., Biol Res 44(3):269-75
[2] Isturiz T., Celaya J., 1997, The metabolism of gluconate in Escherichia coli. The subsidiary system and the nature of the gntS gene., J Basic Microbiol 37(2):105-14
[3] Wang IN., Dykhuizen DE., 2001, Variation of enzyme activities at a branched pathway involved in the utilization of gluconate in Escherichia coli., Evolution 55(5):897-908