RegulonDB

RegulonDB RegulonDB 10.8: Gene Form

narU gene in Escherichia coli K-12 genome

Gene local context to scale (view description)

Gene
Name:	narU
Synonym(s):	ECK1463, EG12153, b1469, yddF
Genome position(nucleotides):	1542672 <-- 1544060 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	48.96
External database links:

ASAP:	ABE-0004901
ECHOBASE:	EB2073
OU-MICROARRAY:	b1469
PortEco:	narU
STRING:	511145.b1469
COLOMBOS:	narU

Product

Name:

nitrate/nitrite transporter NarU

Synonym(s):

NarU, NarU MFS nitrate/nitrite antiporter, YddF

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

49.89

Isoelectric point:

10.584

Motif(s):

Type	Positions	Sequence
	113 -> 113	P
	172 -> 172	G
	207 -> 227	VMSLANAAWIWVPLLAIATIA
	307 -> 307	G
	345 -> 365	FIAFYAVFMGLFLTAGLGSGS

Type	Positions	Sequence
	113 -> 113	P
	172 -> 172	G
	207 -> 227	VMSLANAAWIWVPLLAIATIA
	307 -> 307	G
	345 -> 365	FIAFYAVFMGLFLTAGLGSGS
	175 -> 175	G
	288 -> 308	ILRLAFFGPFIGAIARSVGGA
	290 -> 290	R
	311 -> 311	D
	402 -> 422	AALGFISAIGAVGGFFIPQAF
	433 -> 453	VGAMKVFLIFYIVCVLLTWLV
	77 -> 97	ALPSVSGALLRVPYSFMVPIF
	139 -> 139	G
	293 -> 293	F
	36 -> 56	LWISVSCLLLAFCVWMLFSAV
	43 -> 419	LLLAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAKQGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIASSRASIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFAMLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLFLTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRVKMKGGSDEQAHKEAVTETAAALGFISAIGAVGGFFIP
	99 -> 99	G
	162 -> 162	G
	261 -> 261	Y
	87 -> 87	R
	303 -> 303	R
	405 -> 405	G
	259 -> 279	LLYLATFGSFIGFSAGFAMLA
	266 -> 266	G
	181 -> 201	LVAPLVIFVPVFAFLGVNGVP
	318 -> 338	VTLINFIFMAIFSALLFLTLP
	102 -> 122	WTVFSTAILIIPCVWLGIAVQ
	126 -> 146	TPFGIFIVIALLCGFAGANFA
	145 -> 145	F
	414 -> 414	G

Classification:

Multifun Terms (GenProtEC)
		1 - metabolism --> 1.8 - metabolism of other compounds --> 1.8.3 - nitrogen metabolism
		4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
		6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0005887 - integral component of plasma membrane GO:0016021 - integral component of membrane
	molecular_function	GO:0015112 - nitrate transmembrane transporter activity GO:0015113 - nitrite transmembrane transporter activity GO:0015514 - nitrite efflux transmembrane transporter activity GO:0022857 - transmembrane transporter activity
	biological_process	GO:0015706 - nitrate transport GO:0015707 - nitrite transport GO:0042128 - nitrate assimilation GO:0055085 - transmembrane transport

Note(s):

Note(s): ...[more].

External database links:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

MODBASE:

PDB:

PDB:

PFAM:

PRIDE:

PRODB:

PROSITE:

REFSEQ:

SMR:

UNIPROT:

Operon

Name:

narU

Operon arrangement:

Transcription unit	Promoter
narU	narUp1
narU	narUp2

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	narZp	1542690		reverse	Rpos has been proved to control narZYWV operon transcription under anaerobiosis by Chang L,1999 and a potential σ³⁸ promoter was identified 116 bp upstream the narU start codon. Read more >	[AIPP]	[1]
	promoter	yddJp8	1544758		reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 6.76. P-value: 1.427e-6 Read more >	[ICWHO]	[1]
	promoter	yddJp9	1544763		reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 8.295. P-value: 2.902e-6 Read more >	[ICWHO]	[1]
	promoter	yddJp5	1544825		reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: poor homology. Score: 3.074. P-value: 8.524e-5 Read more >	[ICWHO]	[1]
	promoter	yddJp6	1544851		reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 3.3. P-value: 7.791e-5 Read more >	[ICWHO]	[1]
	promoter	yddJp1	1544866		reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: poor homology. Score: -3.21. P-value: 6.910e-5 Read more >	[ICWHO]	[1]

Evidence
[AIPP] Automated inference of promoter position
[ICWHO] Inferred computationally without human oversight

Reference(s)
[1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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