RegulonDB RegulonDB 10.8: Gene Form
   

ytjC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

rob ytjC yjjX creA NagC SoxS Rob MarA creAp creAp robp robp creAp2 creAp2 TSS_5185 TSS_5185 TSS_5184 TSS_5184 TSS_5183 TSS_5183 yjjXp6 yjjXp6 yjjXp5 yjjXp5 TSS_5181 TSS_5181 TSS_5180 (cluster) TSS_5180 (cluster)

Gene      
Name: ytjC    Texpresso search in the literature
Synonym(s): ECK4387, EG12164, b4395, gpmB
Genome position(nucleotides): 4633797 --> 4634444 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
56.17
External database links:  
ASAP:
ABE-0014416
ECHOBASE:
EB2083
OU-MICROARRAY:
b4395
PortEco:
ytjC
STRING:
511145.b4395
COLOMBOS: ytjC


Product      
Name: putative phosphatase
Synonym(s): GpmB, YtjC
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 24.065
Isoelectric point: 5.372
Motif(s):
 
Type Positions Sequence
104 -> 105 RR
82 -> 85 ELNM
151 -> 152 GI
21 -> 22 QG
4 -> 194 VYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEENWRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLWLASGW

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.3 - energy metabolism, carbon --> 1.3.1 - glycolysis
  1 - metabolism --> 1.7 - central intermediary metabolism
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0003824 - catalytic activity
GO:0016853 - isomerase activity
GO:0004619 - phosphoglycerate mutase activity
biological_process GO:0006096 - glycolytic process
Note(s): Note(s): ...[more].
Reference(s): [1] Khersonsky O., et al., 2011
External database links:  
DIP:
DIP-9829N
ECOCYC:
PGAM2-MONOMER
ECOLIWIKI:
b4395
INTERPRO:
IPR029033
INTERPRO:
IPR023086
INTERPRO:
IPR001345
INTERPRO:
IPR013078
MINT:
MINT-1235576
MODBASE:
P0A7A2
PFAM:
PF00300
PRIDE:
P0A7A2
PROSITE:
PS00175
REFSEQ:
NP_418812
SMART:
SM00855
SMR:
P0A7A2
UNIPROT:
P0A7A2


Operon      
Name: ytjC         
Operon arrangement:
Transcription unit        Promoter
ytjC


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_5180 (cluster) 4633755 forward For this promoter, there
Read more >
[RS-EPT-CBR] [2]
  promoter TSS_5181 4633764 reverse nd [RS-EPT-CBR] [2]
  promoter yjjXp5 4633773 reverse Similarity to the consensus
Read more >
[ICWHO], [RS-EPT-CBR] [2], [3]
  promoter yjjXp6 4633899 reverse Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter TSS_5183 4634537 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_5184 4634582 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_5185 4635151 reverse nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Khersonsky O., Malitsky S., Rogachev I., Tawfik DS., 2011, Role of chemistry versus substrate binding in recruiting promiscuous enzyme functions., Biochemistry 50(13):2683-90

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


RegulonDB