RegulonDB RegulonDB 10.8: Gene Form
   

yhjX gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

eptB yhjX yhjY PyrR PyrR MgrR terminator yhjXp6 yhjXp6 yhjXp5 yhjXp5 yhjXp yhjXp eptBp eptBp

Gene      
Name: yhjX    Texpresso search in the literature
Synonym(s): ECK3534, EG12268, b3547
Genome position(nucleotides): 3710799 <-- 3712007 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
51.2
External database links:  
ASAP:
ABE-0011586
ECHOBASE:
EB2177
OU-MICROARRAY:
b3547
PortEco:
yhjX
STRING:
511145.b3547
COLOMBOS: yhjX


Product      
Name: putative transporter YhjX
Synonym(s): YhjX
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 42.951
Isoelectric point: 9.575
Motif(s):
 
Type Positions Sequence
12 -> 34 LTLIGTIITQFALGSVYTWSLFN
217 -> 236 WMLAVMFLTACMSGLYVIGV
342 -> 364 YGVIYLGFGIGSICGSIIASLFG
73 -> 95 FGVKRVTMASGILLGLGFFLTAH
368 -> 387 VTFYVIFALLILSLALSTTI

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0005515 - protein binding
GO:0022857 - transmembrane transporter activity
GO:0042802 - identical protein binding
biological_process GO:0031669 - cellular response to nutrient levels
GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Evidence: [HIFS] Human inference of function from sequence
[IEP] Inferred from expression pattern
Reference(s): [1] Behr S., et al., 2014
[2] Fried L., et al., 2013
[3] Jindal S., et al., 2019
[4] Pao SS., et al., 1998
[5] Zhou S., et al., 2019
External database links:  
DIP:
DIP-12395N
ECOCYC:
YHJX-MONOMER
ECOLIWIKI:
b3547
INTERPRO:
IPR011701
INTERPRO:
IPR036259
INTERPRO:
IPR020846
INTERPRO:
IPR004741
MINT:
MINT-1232452
MODBASE:
P37662
PFAM:
PF07690
PRIDE:
P37662
PROSITE:
PS50850
REFSEQ:
NP_418003
SMR:
P37662
UNIPROT:
P37662


Operon      
Name: yhjX         
Operon arrangement:
Transcription unit        Promoter
yhjX


Transcriptional Regulation      
Display Regulation             
Activated by: PyrR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yhjXp5 3712060 reverse Similarity to the consensus
Read more >
[ICWHO] [6]
  promoter yhjXp6 3712097 reverse Similarity to the consensus
Read more >
[ICWHO] [6]


Evidence    

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Behr S., Fried L., Jung K., 2014, Identification of a novel nutrient-sensing histidine kinase/response regulator network in Escherichia coli., J Bacteriol 196(11):2023-9

 [2] Fried L., Behr S., Jung K., 2013, Identification of a Target Gene and Activating Stimulus for the YpdA/YpdB Histidine Kinase/Response Regulator System in Escherichia coli., J Bacteriol 195(4):807-15

 [3] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

 [4] Pao SS., Paulsen IT., Saier MH., 1998, Major facilitator superfamily., Microbiol Mol Biol Rev 62(1):1-34

 [5] Zhou S., Zhuang Y., Zhu X., Yao F., Li H., Zou X., Wu J., Zhou H., Nuer G., Huang Y., Li S., Peng Q., 2019, YhjX Regulates the Growth of Escherichia coli in the Presence of a Subinhibitory Concentration of Gentamicin and Mediates the Adaptive Resistance to Gentamicin., Front Microbiol 10:1180

 [6] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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