RegulonDB RegulonDB 10.9: Gene Form
   

aldB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

aldB yiaY yiaW Fis Fis Fis CRP Fis Fis anti-anti-terminator anti-terminator terminator aldBp aldBp

Gene      
Name: aldB    Texpresso search in the literature
Synonym(s): ECK3577, EG12292, b3588, yiaX
Genome position(nucleotides): 3754973 <-- 3756511 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
54.78
Reference(s): [1] Xu J., et al., 1995
External database links:  
ASAP:
ABE-0011718
CGSC:
35668
ECHOBASE:
EB2200
ECOLIHUB:
aldB
OU-MICROARRAY:
b3588
STRING:
511145.b3588
COLOMBOS: aldB


Shine dalgarno      
Sequence: ctcacaccgcAAGGAGacgatCAT


Product      
Name: aldehyde dehydrogenase B
Synonym(s): AldB, YiaX
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 56.306
Isoelectric point: 5.359
Motif(s):
 
Type Positions Sequence
197 -> 197 R
33 -> 498 WVAPADGEYYQNLTPVTGQLLCEVASSGKRDIDLALDAAHKVKDKWAHTSVQDRAAILFKIADRMEQNLELLATAETWDNGKPIRETSAADVPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEPLGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEIVGDLLPPGVVNVVNGAGGVIGEYLATSKRIAKVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNIFFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIYERFMERAIRRVESIRSGNPLDSVTQMGAQVSHGQLETILNYIDIGKKEGADVLTGGRRKLLEGELKDGYYLEPTILFGQNNMRVFQEEIFGPVLAVTTFKTMEEALELANDTQYGLGAGVWSRNGNLAYKMGRGIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLEHYQQTK

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0016491 - oxidoreductase activity
GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0033721 - aldehyde dehydrogenase (NADP+) activity
GO:0004029 - aldehyde dehydrogenase (NAD+) activity
biological_process GO:0006974 - cellular response to DNA damage stimulus
GO:0055114 - oxidation-reduction process
GO:0045471 - response to ethanol
External database links:  
DIP:
DIP-9082N
ECOCYC:
ALDDEHYDROGB-MONOMER
ECOLIWIKI:
b3588
INTERPRO:
IPR029510
INTERPRO:
IPR016162
INTERPRO:
IPR016161
INTERPRO:
IPR016163
INTERPRO:
IPR015590
INTERPRO:
IPR016160
MINT:
P37685
MODBASE:
P37685
PFAM:
PF00171
PRIDE:
P37685
PRODB:
PRO_000022076
PROSITE:
PS00687
PROSITE:
PS00070
REFSEQ:
NP_418045
SMR:
P37685
UNIPROT:
P37685


Operon      
Name: aldB         
Operon arrangement:
Transcription unit        Promoter
aldB


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: Fis


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Xu J., Johnson RC., 1995, aldB, an RpoS-dependent gene in Escherichia coli encoding an aldehyde dehydrogenase that is repressed by Fis and activated by Crp., J Bacteriol 177(11):3166-75


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