RegulonDB RegulonDB 10.8: Gene Form
   

coaE gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

zapD coaE yacG b0100 yacM TSS_229 TSS_229 TSS_228 TSS_228 TSS_227 TSS_227 TSS_226 TSS_226 TSS_225 TSS_225 TSS_224 TSS_224 TSS_223 TSS_223 TSS_222 TSS_222

Gene      
Name: coaE    Texpresso search in the literature
Synonym(s): ECK0103, EG12312, b0103, yacE
Genome position(nucleotides): 112599 <-- 113219 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
52.66
External database links:  
ASAP:
ABE-0000357
ECHOBASE:
EB2218
OU-MICROARRAY:
b0103
PortEco:
coaE
STRING:
511145.b0103
COLOMBOS: coaE


Product      
Name: dephospho-CoA kinase
Synonym(s): CoaE, YacE
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 22.622
Isoelectric point: 6.148
Motif(s):
 
Type Positions Sequence
4 -> 200 IVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGAPALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQATREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQF
12 -> 17 GSGKST
72 -> 74 ERI
86 -> 86 A
3 -> 177 YIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGAPALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQATREARLAVADDVIDNNG

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.3 - cofactors, small molecule carriers --> 1.5.3.5 - Coenzyme A and its modification
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
molecular_function GO:0016740 - transferase activity
GO:0016301 - kinase activity
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0004140 - dephospho-CoA kinase activity
biological_process GO:0015937 - coenzyme A biosynthetic process
GO:0016310 - phosphorylation
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-47935N
ECOCYC:
EG12312-MONOMER
ECOLIWIKI:
b0103
INTERPRO:
IPR001977
INTERPRO:
IPR027417
MODBASE:
P0A6I9
PDB:
6ARI
PDB:
1VHT
PDB:
1VHL
PDB:
1T3H
PDB:
1N3B
PDB:
1VIY
PFAM:
PF01121
PRIDE:
P0A6I9
PRODB:
PRO_000022311
PROSITE:
PS51219
REFSEQ:
NP_414645
SMR:
P0A6I9
UNIPROT:
P0A6I9


Operon      
Name: coaE-zapD-yacG         
Operon arrangement:
Transcription unit        Promoter
yacG
 


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_222 112251 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_223 112273 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_224 112599 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_225 112607 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_226 112609 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_227 112617 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_228 112696 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_229 112703 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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