RegulonDB RegulonDB 10.6.3: Gene Form
   

lhgD gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

gabD lhgD glaH Nac gabDp1 gabDp1 gabDp2 gabDp2

Gene      
Name: lhgD    Texpresso search in the literature
Synonym(s): ECK2654, EG12387, b2660, lhgO, ygaF
Genome position(nucleotides): 2789982 --> 2791250 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
57.68
External database links:  
ASAP:
ABE-0008756
ECHOBASE:
EB2288
ECOCYC:
EG12387
ECOLIHUB:
lhgO
MIM:
236792
OU-MICROARRAY:
b2660
REGULONDB:
b2660
STRING:
511145.b2660
M3D: lhgD
COLOMBOS: lhgD
PortEco: b2660


Product      
Name: L-2-hydroxyglutarate dehydrogenase
Synonym(s): LhgD, LhgO, YgaF
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane,cytosol
Molecular weight: 46.082
Isoelectric point: 8.463
Motif(s):
 
Type Positions Sequence
3 -> 390 DFVIIGGGIIGMSTAMQLIDVYPDARIALLEKESAPACHQTGHNSGVIHAGVYYTPGSLKAQFCLAGNRATKAFCDQNGIRYDNCGKMLVATSDLEMERMRALWERTAANGIEREWLNADELREREPNITGLGGIFVPSSGIVSYRDVTAAMAKIFQSRGGEIIYNAEVSGLNEHKNGVVIRTRQGGEYEASTLISCSGLMADRLVKMLGLEPGFIICPFRGEYFRLAPEHNQIVNHLIYPIPDPAMPFLGVHLTRMIDGSVTVGPNAVLAFKREGYRKRDFSFSDTLEILGSSGIRRVLQNHLRSGLGEMKNSLCKSGYLRLVQKYCPRLSLSDLQPWPAGVRAQAVSPDGKLIDDFLFVTTPRTIHTCNAPSPAATSAIPIGAHIV

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.3 - amino acids
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
molecular_function GO:0005515 - protein binding
GO:0016491 - oxidoreductase activity
GO:0047545 - 2-hydroxyglutarate dehydrogenase activity
GO:0050660 - flavin adenine dinucleotide binding
GO:0003973 - (S)-2-hydroxy-acid oxidase activity
GO:0034419 - L-2-hydroxyglutarate oxidase activity
biological_process GO:0055114 - oxidation-reduction process
GO:0006554 - lysine catabolic process
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-12096N
ECOCYC:
EG12387-MONOMER
ECOLIWIKI:
b2660
INTERPRO:
IPR036188
INTERPRO:
IPR030862
INTERPRO:
IPR006076
MINT:
MINT-1301841
MODBASE:
P37339
PFAM:
PF01266
PRIDE:
P37339
PROTEINMODELPORTAL:
P37339
REFSEQ:
NP_417146
SMR:
P37339
UNIPROT:
P37339


Operon      
Name: glaH-lhgD-gabDTP         
Operon arrangement:
Transcription unit        Promoter
csiD-ygaF-gabDTP
gabDTP
gabDTP


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, H-NS, Lrp
Repressed by: GlaR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



RegulonDB