RegulonDB RegulonDB 10.8: Gene Form
   

gatD gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

gatC gatD insEF5 insF5 gatB insE5 TSS_2410 TSS_2410 TSS_2409 (cluster) TSS_2409 (cluster) TSS_2408 TSS_2408 TSS_2407 TSS_2407 TSS_2406 (cluster) TSS_2406 (cluster)

Gene      
Name: gatD    Texpresso search in the literature
Synonym(s): ECK2084, EG12417, b2091
Genome position(nucleotides): 2171833 <-- 2172873 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 48.8
External database links:  
ASAP:
 ABE-0006924
CGSC:
 713
ECHOBASE:
 EB2316
OU-MICROARRAY:
 b2091
PortEco:
 gatD
STRING:
 511145.b2091
COLOMBOS: gatD


Product      
Name: galactitol-1-phosphate 5-dehydrogenase
Synonym(s): GatD
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 37.39
Isoelectric point: 6.338
Motif(s):
 
Type Positions Sequence
226 -> 227 EL
271 -> 271 A
327 -> 329 AQA
222 -> 222 S
213 -> 213 S

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0046872 - metal ion binding
GO:0016491 - oxidoreductase activity
GO:0008270 - zinc ion binding
GO:0008868 - galactitol-1-phosphate 5-dehydrogenase activity
GO:0042802 - identical protein binding
GO:0042803 - protein homodimerization activity
biological_process GO:0019402 - galactitol metabolic process
GO:0019404 - galactitol catabolic process
GO:0055114 - oxidation-reduction process
External database links:  
DIP:
 DIP-47890N
ECOCYC:
 GALACTITOLPDEHYD-MONOMER
ECOLIWIKI:
 b2091
INTERPRO:
 IPR020843
INTERPRO:
 IPR036291
INTERPRO:
 IPR013154
INTERPRO:
 IPR013149
INTERPRO:
 IPR011032
INTERPRO:
 IPR002328
MINT:
 P0A9S3
MODBASE:
 P0A9S3
PANTHER:
 PTHR11695
PDB:
 4A2C
PDB:
 4UEO
PDB:
 4UEK
PDB:
 4UEJ
PFAM:
 PF00107
PFAM:
 PF08240
PRIDE:
 P0A9S3
PRODB:
 PRO_000022756
PROSITE:
 PS00059
REFSEQ:
 NP_416594
SMART:
 SM00829
SMR:
 P0A9S3
UNIPROT:
 P0A9S3


Operon      
Name: gatYZABCD         
Operon arrangement:
Transcription unit        Promoter
gatZABCD
gatYZABCD


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: ArcA, GatR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2406 (cluster) 2172607 reverse For this promoter, there
Read more > 		[RS-EPT-CBR] [1]
  promoter TSS_2407 2174427 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2408 2174431 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2409 (cluster) 2174473 reverse For this promoter, there
Read more > 		[RS-EPT-CBR] [1]
  promoter TSS_2410 2174500 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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