RegulonDB RegulonDB 10.7: Gene Form
   

gntU gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

gntU yhgN gntK gntUp2 gntUp2

Gene      
Name: gntU    Texpresso search in the literature
Synonym(s): ECK3421, EG12631, b3435, b3436, b4476
Genome position(nucleotides): 3575721 <-- 3577061 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
55.03
External database links:  
ASAP:
ABE-0174105
CGSC:
35461
ECHOBASE:
EB2515
OU-MICROARRAY:
b3436
PORTECO:
gntU
REGULONDB:
b4476
STRING:
511145.b4476
M3D: gntU
COLOMBOS: gntU
PortEco: b3436


Shine dalgarno      
Sequence: tattaaaaaaGGCAAAtaagtAGT


Product      
Name: low-affinity gluconate transporter
Synonym(s): GntU
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 46.416
Isoelectric point: 7.044
Motif(s):
 
Type Positions Sequence
295 -> 315 ICGHALQPAGIILLVIGAGGV
425 -> 445 MMETILGTVGAIVGMIAFQLL
5 -> 441 TLVLTAVGSVLLLLFLVMKARMHAFLALMVVSMGAGLFSGMPLDKIAATMEKGMGGTLGFLAVVVALGAMFGKILHETGAVDQIAVKMLKSFGHSRAHYAIGLAGLVCALPLFFEVAIVLLISVAFSMARHTGTNLVKLVIPLFAGVAAAAAFLVPGPAPMLLASQMNADFGWMILIGLCAAIPGMIIAGPLWGNFISRYVELHIPDDISEPHLGEGKMPSFGFSLSLILLPLVLVGLKTIAARFVPEGSTAYEWFEFIGHPFTAILVACLVAIYGLAMRQGMPKDKVMEICGHALQPAGIILLVIGAGGVFKQVLVDSGVGPALGEALTGMGLPIAITCFVLAAAVRIIQGSATVACLTAVGLVMPVIEQLNYSGAQMAALSICIAGGSIVVSHVNDAGFWLFGKFTGATEAETLKTWTMMETILGTVGAIVGMIA
262 -> 282 FIGHPFTAILVACLVAIYGLA
331 -> 351 EALTGMGLPIAITCFVLAAAV

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0005402 - carbohydrate:cation symporter activity
GO:0015128 - gluconate transmembrane transporter activity
biological_process GO:0008643 - carbohydrate transport
GO:0019521 - D-gluconate metabolic process
GO:0035429 - gluconate transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
GNTU-MONOMER
ECOLIWIKI:
b4476
INTERPRO:
IPR003474
PANTHER:
PTHR30354
PFAM:
PF02447
PRIDE:
P0AC96
PRODB:
PRO_000022827
PROTEINMODELPORTAL:
P0AC96
REFSEQ:
YP_026221
UNIPROT:
P0AC96


Operon      
Name: gntRKU         
Operon arrangement:
Transcription unit        Promoter
gntK
gntKU
gntR
gntR
gntR
gntRKU
 


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: GntR, IdnR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter gntUp2 3577085 reverse Similarity to the consensus
Read more >
[ICWHO] [1]


Evidence    

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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