RegulonDB RegulonDB 10.8: Gene Form
   

sstT gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

sstT alx ygjV GcvB terminator anti-terminator anti-anti-terminator TSS_3388 TSS_3388 TSS_3387 TSS_3387 TSS_3386 TSS_3386 TSS_3385 TSS_3385 TSS_3384 TSS_3384 TSS_3383 TSS_3383 sstTp sstTp

Gene      
Name: sstT    Texpresso search in the literature
Synonym(s): ECK3080, EG12732, b3089, ygjU
Genome position(nucleotides): 3239944 --> 3241188 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 55.18
External database links:  
ASAP:
 ABE-0010159
ECHOBASE:
 EB2590
OU-MICROARRAY:
 b3089
PortEco:
 sstT
STRING:
 511145.b3089
COLOMBOS: sstT


Product      
Name: serine/threonine:Na+ symporter
Synonym(s): SstT, SstT DAACS transporter, YgjU
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 43.478
Isoelectric point: 8.58
Motif(s):
 
Type Positions Sequence
2 -> 414 TTQRSPGLFRRLAHGSLVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPILVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAGDISPPSGIVEVMRGLVMSMVSNPIDALLKGNYIGILVWAIGLGFALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAQLLVVLVGCMLLVALVVNPLLVWWKIRRNPFPLVLLCLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVNTLGIPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGISNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAACQAEDDRLANSALRN
300 -> 320 MAGAAITITVLTLAAVNTLGI
18 -> 397 LVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPILVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAGDISPPSGIVEVMRGLVMSMVSNPIDALLKGNYIGILVWAIGLGFALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAQLLVVLVGCMLLVALVVNPLLVWWKIRRNPFPLVLLCLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVNTLGIPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGISNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTA
143 -> 163 ALLKGNYIGILVWAIGLGFAL
46 -> 66 LGTLFVGALKAVAPILVLMLV

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.11 - serine
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.8 - threonine
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015293 - symporter activity
GO:0015171 - amino acid transmembrane transporter activity
GO:0022857 - transmembrane transporter activity
GO:0015175 - neutral amino acid transmembrane transporter activity
GO:0005295 - neutral amino acid:sodium symporter activity
biological_process GO:0006865 - amino acid transport
GO:0055085 - transmembrane transport
GO:0032329 - serine transport
GO:0003333 - amino acid transmembrane transport
GO:0015826 - threonine transport
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
 YGJU-MONOMER
ECOLIWIKI:
 b3089
INTERPRO:
 IPR001991
INTERPRO:
 IPR036458
INTERPRO:
 IPR023025
PANTHER:
 PTHR11958
PFAM:
 PF00375
PRIDE:
 P0AGE4
PRINTS:
 PR00173
PRODB:
 PRO_000023994
PROSITE:
 PS00713
REFSEQ:
 NP_417560
SMR:
 P0AGE4
UNIPROT:
 P0AGE4


Operon      
Name: sstT         
Operon arrangement:
Transcription unit        Promoter
sstT


RNA cis-regulatory element    
Attenuation: Transcriptional


Regulation by small RNA    
  Display Regulation
small RNA gcvB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3383 3239984 forward nd [RS-EPT-CBR] [1]
  promoter TSS_3384 3240007 forward nd [RS-EPT-CBR] [1]
  promoter TSS_3385 3240085 forward nd [RS-EPT-CBR] [1]
  promoter TSS_3386 3240529 forward nd [RS-EPT-CBR] [1]
  promoter TSS_3387 3240567 forward nd [RS-EPT-CBR] [1]
  promoter TSS_3388 3240667 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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