RegulonDB RegulonDB 11.1: Gene Form
   

yhdZ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yhdY yhdZ rrfF

Gene      
Name: yhdZ    Texpresso search in the literature
Synonym(s): ECK3258, EG12837, b3271
Genome position(nucleotides): 3422436 --> 3423194
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 47.04
External database links:  
ASAP:
 ABE-0010738
ECHOBASE:
 EB2686
ECOLIHUB:
 yhdZ
OU-MICROARRAY:
 b3271
STRING:
 511145.b3271
COLOMBOS: yhdZ


Product      
Name: putative ABC transporter ATP-binding subunit YhdZ
Synonym(s): YhdZ
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane,cytosol
Molecular weight: 28.574
Isoelectric point: 7.102
Motif(s):
 
Type Positions Sequence Comment
13 -> 247 ITLENVNKWYGQFHVLKNINLTVQPGERIVLCGPSGSGKSTTIRCINHLEEHQQGRIVVDGIELNEDIRNIERVRQEVGMVFQHFNLFPHLTVLQNCTLAPIWVRKMPKKEAEDLAVHYLERVRIAEHAHKFPGQISGGQQQRVAIARSLCMKPKIMLFDEPTSALDPEMVKEVLDTMIGLAQSGMTMLCVTHEMGFARTVADRVIFMDRGEIVEQAAPDEFFAHPKSERTRAFL UniProt: ABC transporter.
28 -> 176 LKNINLTVQPGERIVLCGPSGSGKSTTIRCINHLEEHQQGRIVVDGIELNEDIRNIERVRQEVGMVFQHFNLFPHLTVLQNCTLAPIWVRKMPKKEAEDLAVHYLERVRIAEHAHKFPGQISGGQQQRVAIARSLCMKPKIMLFDEPTS
45 -> 52 GPSGSGKS UniProt: ATP.
168 -> 175 IMLFDEPT

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.a - ABC superfamily ATP binding cytoplasmic component
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0043190 - ATP-binding cassette (ABC) transporter complex
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
molecular_function GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0015424 - ABC-type amino acid transporter activity
biological_process GO:0006865 - amino acid transport
GO:0015833 - peptide transport
GO:0003333 - amino acid transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Jindal S., et al., 2019
External database links:  
ALPHAFOLD:
 P45769
ECOCYC:
 YHDZ-MONOMER
ECOLIWIKI:
 b3271
INTERPRO:
 IPR003439
INTERPRO:
 IPR003593
INTERPRO:
 IPR017871
INTERPRO:
 IPR027417
INTERPRO:
 IPR030679
MODBASE:
 P45769
PFAM:
 PF00005
PRIDE:
 P45769
PROSITE:
 PS00211
PROSITE:
 PS50893
REFSEQ:
 NP_417737
SMART:
 SM00382
SMR:
 P45769
SWISSMODEL:
 P45769
UNIPROT:
 P45769


Operon      
Name: yhdWXYZ         
Operon arrangement:
Transcription unit        Promoter
yhdWXYZ


Transcriptional Regulation      
Display Regulation             
Activated by: NtrC


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

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