RegulonDB RegulonDB 10.7: Gene Form
   

lysW gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

valT lysW valZ Cis-reg TSS_898 TSS_898

Gene      
Name: lysW    Texpresso search in the literature
Synonym(s): ECK0734, EG30057, b0745, lysT-beta, lysTbeta, su
Genome position(nucleotides): 780843 --> 780918 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
50.0
External database links:  
ASAP:
ABE-0002529
CGSC:
28352
ECHOBASE:
EB4220
OU-MICROARRAY:
b0745
PORTECO:
lysW
REGULONDB:
b0745
M3D: lysW
COLOMBOS: lysW
PortEco: b0745


Product      
Name: tRNA-Lys(UUU)
Synonym(s): tRNAlysW
Type: tRNAs
Cellular location: cytosol
Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.2 - RNA related --> 2.2.5 - tRNA
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0030533 - triplet codon-amino acid adaptor activity
Note(s): Note(s): ...[more].
Evidence: [TAS] Traceable author statement
Reference(s): [1] Murphy FV., et al., 2004
[2] Siekevitz P., et al., 1981
External database links:  
ECOCYC:
lysW-tRNA
ECOLIWIKI:
b0745


Operon      
Name: lysT-valT-lysW         
Operon arrangement:
Transcription unit        Promoter
lysT-valT-lysW


Transcriptional Regulation      
Display Regulation             
Activated by: Fis


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_898 780920 forward nd [RS-EPT-CBR] [3]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Murphy FV., Ramakrishnan V., Malkiewicz A., Agris PF., 2004, The role of modifications in codon discrimination by tRNA(Lys)UUU., Nat Struct Mol Biol 11(12):1186-91

 [2] Siekevitz P., Zamecnik PC., 1981, Ribosomes and protein synthesis., J Cell Biol 91(3 Pt 2):53s-65s

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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