RegulonDB RegulonDB 10.8: Gene Form
   

metY gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

argG rimP metY ArgR ArgR ArgR CRP Fis anti-anti-terminator anti-terminator terminator TSS_3475 TSS_3475 TSS_3474 (cluster) TSS_3474 (cluster) TSS_3473 TSS_3473 argGp argGp metYp2 metYp2 metYp1 metYp1 rimPp rimPp TSS_3471 TSS_3471 TSS_3470 TSS_3470 TSS_3469 (cluster) TSS_3469 (cluster) TSS_3468 TSS_3468 TSS_3467 (cluster) TSS_3467 (cluster) nusAp nusAp

Gene      
Name: metY    Texpresso search in the literature
Synonym(s): ECK3160, EG30061, b3171
Genome position(nucleotides): 3318213 <-- 3318289 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
64.94
External database links:  
ASAP:
ABE-0010420
CGSC:
504
ECHOBASE:
EB4224
OU-MICROARRAY:
b3171
PortEco:
metY
COLOMBOS: metY


Product      
Name: tRNA-initiator Met(CAU)
Synonym(s): tRNAfMet2, tRNAmetY
Type: tRNAs
Cellular location: cytosol
Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.2 - RNA related --> 2.2.5 - tRNA
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0030533 - triplet codon-amino acid adaptor activity
Note(s): Note(s): ...[more].
Evidence: [TAS] Traceable author statement
Reference(s): [1] Shetty S., et al., 2016
[2] Siekevitz P., et al., 1981
External database links:  
ECOCYC:
metY-tRNA
ECOLIWIKI:
b3171


Operon      
Name: metY-rimP-nusA-infB-rbfA-truB-rpsO-pnp         
Operon arrangement:
Transcription unit        Promoter
pnp
rpsO
rpsO-pnp
infB
nusA-infB
rimP-nusA-infB
metY
metY-yhbC-nusA-infB
metY-yhbC-nusA-infB-rbfA-truB-rpsO-pnp
metY
metY-yhbC-nusA-infB-rbfA-truB-rpsO-pnp


Transcriptional Regulation      
Display Regulation             
Activated by: Fis
Repressed by: CRP, ArgR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3467 (cluster) 3317609 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [3]
  promoter TSS_3468 3317627 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3469 (cluster) 3317768 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [3]
  promoter TSS_3470 3317880 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3471 3317926 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_3473 3318996 forward nd [RS-EPT-CBR] [3]
  promoter TSS_3474 (cluster) 3318998 forward For this promoter, there
Read more >
[RS-EPT-CBR] [3]
  promoter TSS_3475 3319007 forward nd [RS-EPT-CBR] [3]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Shetty S., Varshney U., 2016, An evolutionarily conserved element in initiator tRNAs prompts ultimate steps in ribosome maturation., Proc Natl Acad Sci U S A 113(41):E6126-E6134

 [2] Siekevitz P., Zamecnik PC., 1981, Ribosomes and protein synthesis., J Cell Biol 91(3 Pt 2):53s-65s

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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