RegulonDB RegulonDB 10.8: Gene Form
   

tyrT gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

purU tyrT tyrV Fis Fis Fis ppGpp Cis-reg TSS_1557 TSS_1557 TSS_1556 TSS_1556 tyrTp tyrTp

Gene      
Name: tyrT    Texpresso search in the literature
Synonym(s): ECK1226, EG30106, Su-3, Su-4, b1231, su(c), suIII, supC, supFsupO, tyrTalpha
Genome position(nucleotides): 1287538 <-- 1287622 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
58.82
External database links:  
ASAP:
ABE-0004136
CGSC:
53
ECHOBASE:
EB4269
OU-MICROARRAY:
b1231
PortEco:
tyrT
COLOMBOS: tyrT


Product      
Name: tRNA-Tyr(GUA)
Synonym(s): tRNAtyrT
Type: tRNAs
Cellular location: cytosol
Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.2 - RNA related --> 2.2.5 - tRNA
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0030533 - triplet codon-amino acid adaptor activity
Note(s): Note(s): ...[more].
Evidence: [TAS] Traceable author statement
Reference(s): [1] Abelson J., et al., 1969
[2] Addepalli B., et al., 2016
[3] Siekevitz P., et al., 1981
External database links:  
ECOCYC:
tyrT-tRNA
ECOLIWIKI:
b1231


Operon      
Name: tyrTV-tpr         
Operon arrangement:
Transcription unit        Promoter
tyrTV-tpr
tyrV-tpr


Transcriptional Regulation      
Display Regulation             
Activated by: Fis
Growth Conditions:

[1] 

C: Escherichia coli| minimal medium| glucose| 37.0 C| mid exponential phase
E: Escherichia coli| minimal medium| glucose; novobiocin 12.5 µg/mL| 37.0 C| mid exponential phase



Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1556 1288063 reverse nd [RS-EPT-CBR] [4]
  promoter TSS_1557 1288077 reverse nd [RS-EPT-CBR] [4]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Abelson J., Barnett L., Brenner S., Gefter M., Landy A., Russell R., Smith JD., 1969, Mutant tyrosine transfer ribonucleic acids., FEBS Lett 3(1):1-4

 [2] Addepalli B., Limbach PA., 2016, Pseudouridine in the Anticodon of Escherichia coli tRNATyr(QΨA) Is Catalyzed by the Dual Specificity Enzyme RluF., J Biol Chem 291(42):22327-22337

 [3] Siekevitz P., Zamecnik PC., 1981, Ribosomes and protein synthesis., J Cell Biol 91(3 Pt 2):53s-65s

 [4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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