RegulonDB RegulonDB 10.8: Gene Form
   

sroC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

insH3 gltI gltJ sroC FlhDC FlhDC GcvB anti-anti-terminator anti-terminator terminator gltIp1 gltIp1 TSS_780 TSS_780 TSS_779 (cluster) TSS_779 (cluster) TSS_778 TSS_778

Gene      
Name: sroC    Texpresso search in the literature
Synonym(s): ECK4620, G0-9383, HB_314, b4763
Genome position(nucleotides): 686681 <-- 686843 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
50.31
External database links:  
PortEco:
sroC
COLOMBOS: sroC


Product      
Name: SroC
Synonym(s): HB_314, ig:413, small regulatory RNA SroC
Type: small RNA
Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.2 - RNA related
Gene Ontology Terms (GO)  
biological_process GO:1900191 - negative regulation of single-species biofilm formation
Note(s): Note(s): ...[more].
Evidence: [IDA] Inferred from direct assay
[IMP] Inferred from mutant phenotype
Reference(s): [1] Azam MS., et al., 2015
[2] Bak G., et al., 2015
[3] Frohlich KS., et al., 2018
[4] Vogel J., et al., 2003
External database links:  
ECOCYC:
RNA0-124


Operon      
Name: gltI-sroC-gltJKL         
Operon arrangement:
Transcription unit        Promoter
gltIJKL-sroC
gltI-sroC-gltJKL


Transcriptional Regulation      
Display Regulation             
Activated by: FlhDC


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_778 687847 reverse nd [RS-EPT-CBR] [5]
  promoter TSS_779 (cluster) 687855 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [5]
  promoter TSS_780 687863 reverse nd [RS-EPT-CBR] [5]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Azam MS., Vanderpool CK., 2015, Talk among yourselves: RNA sponges mediate cross talk between functionally related messenger RNAs., EMBO J 34(11):1436-8

 [2] Bak G., Lee J., Suk S., Kim D., Young Lee J., Kim KS., Choi BS., Lee Y., 2015, Identification of novel sRNAs involved in biofilm formation, motility, and fimbriae formation in Escherichia coli., Sci Rep 5:15287

 [3] Frohlich KS., Gottesman S., 2018, Small Regulatory RNAs in the Enterobacterial Response to Envelope Damage and Oxidative Stress., Microbiol Spectr 6(4)

 [4] Vogel J., Bartels V., Tang TH., Churakov G., Slagter-Jager JG., Huttenhofer A., Wagner EG., 2003, RNomics in Escherichia coli detects new sRNA species and indicates parallel transcriptional output in bacteria., Nucleic Acids Res 31(22):6435-43

 [5] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


RegulonDB