RegulonDB RegulonDB 10.8: Gene Form
   

ecnB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

gdx ecnB ecnA blc OmpR Cis-reg terminator TSS_4966 TSS_4966 sugEp sugEp ecnBp ecnBp

Gene      
Name: ecnB    Texpresso search in the literature
Synonym(s): ECK4143, G0-9562, b4411, yjeU
Genome position(nucleotides): 4376553 --> 4376699 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
48.3
External database links:  
ASAP:
ABE-0047211
ECHOBASE:
EB4091
PortEco:
ecnB
STRING:
511145.b4411
COLOMBOS: ecnB


Product      
Name: bacteriolytic entericidin B lipoprotein
Synonym(s): EcnB, YjeU
Sequence: Get amino acid sequence Fasta Format
Cellular location: outer membrane,inner membrane
Molecular weight: 4.81
Isoelectric point: 8.536
Motif(s):
 
Type Positions Sequence
1 -> 21 MVKKTIAAIFSVLVLSTVLTA
24 -> 43 TTRGVGEDISDGGNAISGAA

 

Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes --> 5.5 - adaptations --> 5.5.1 - osmotic pressure
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0036405 - anchored component of cell outer membrane
biological_process GO:0009636 - response to toxic substance
Note(s): Note(s): ...[more].
Evidence: [AUPEINH] Assay of unpurified protein expressed in its native host
Reference(s): [1] Alix E., et al., 2009
[2] Bishop RE., et al., 1998
[3] Gonnet P., et al., 2004
[4] Schellhorn HE., et al., 1998
External database links:  
ECOCYC:
MONOMER0-1563
ECOLIWIKI:
b4411
INTERPRO:
IPR012556
PFAM:
PF08085
PRIDE:
P0ADB7
PROSITE:
PS51257
REFSEQ:
YP_026284
UNIPROT:
P0ADB7


Operon      
Name: ecnAB         
Operon arrangement:
Transcription unit        Promoter
ecnB
 


Transcriptional Regulation      
Display Regulation             
Repressed by: OmpR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4966 4376799 forward nd [RS-EPT-CBR] [5]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Alix E., Blanc-Potard AB., 2009, Hydrophobic peptides: novel regulators within bacterial membrane., Mol Microbiol 72(1):5-11

 [2] Bishop RE., Leskiw BK., Hodges RS., Kay CM., Weiner JH., 1998, The entericidin locus of Escherichia coli and its implications for programmed bacterial cell death., J Mol Biol 280(4):583-96

 [3] Gonnet P., Rudd KE., Lisacek F., 2004, Fine-tuning the prediction of sequences cleaved by signal peptidase II: a curated set of proven and predicted lipoproteins of Escherichia coli K-12., Proteomics 4(6):1597-613

 [4] Schellhorn HE., Audia JP., Wei LI., Chang L., 1998, Identification of conserved, RpoS-dependent stationary-phase genes of Escherichia coli., J Bacteriol 180(23):6283-91

 [5] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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