RegulonDB RegulonDB 10.8: Gene Form
   

mmuP gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

mmuP afuC insH1 mmuM terminator anti-terminator anti-anti-terminator mmuPp2 mmuPp2 insHp5 insHp5 mmuPp5 mmuPp5 mmuPp7 mmuPp7 mmuPp6 mmuPp6 mmuPp1 mmuPp1 TSS_466 TSS_466

Gene      
Name: mmuP    Texpresso search in the literature
Synonym(s): ECK0262, G6135, b0260, ykfD
Genome position(nucleotides): 275325 --> 276728 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 54.84
External database links:  
ASAP:
 ABE-0000893
ECHOBASE:
 EB3126
OU-MICROARRAY:
 b0260
PortEco:
 mmuP
STRING:
 511145.b0260
COLOMBOS: mmuP


Product      
Name: CP4-6 prophage; S-methyl-L-methionine transporter
Synonym(s): MmuP, YkfD
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 50.526
Isoelectric point: 8.536
Motif(s):
 
Type Positions Sequence
43 -> 63 TGAAGTLLAYLIGALVVWLVM
18 -> 451 HLIMLSLGGVIGTGLFFNTGYIISTTGAAGTLLAYLIGALVVWLVMQCLGELSVAMPETGAFHVYAARYLGPATGYTVAWLYWLTWTVALGSSFTAAGFCMQYWFPQVPVWVWCVVFCAIIFGLNVISTRFFAEGEFWFSLVKVVTIIAFIILGGAAIFGFIPMQDGSPAPGLSNITAEGWFPHGGLPILMTMVAVNFAFSGTELIGIAAGETENPRKVIPVAIRTTIARLIIFFIGTVFVLAALIPMQQVGVEKSPFVLVFEKVGIPYAADIFNFVILTAILSAANSGLYASGRMLWSLSNERTLPACFARVTKNGVPLTALSVSMLGGVLALFSSVVAPDTVFVALSAISGFAVVAVWLSICASHFVFRRRHLQQGKALSELHYRAPWYPLVPVLGFVLCLVACVGLAFDPAQRIALWCGLPFVALCYGAYF
96 -> 116 AWLYWLTWTVALGSSFTAAGF
245 -> 265 IARLIIFFIGTVFVLAALIPM
337 -> 357 LTALSVSMLGGVLALFSSVVA

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.9 - methionine
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
  8 - extrachromosomal --> 8.1 - prophage genes and phage related functions
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015171 - amino acid transmembrane transporter activity
GO:0022857 - transmembrane transporter activity
GO:0000100 - S-methylmethionine transmembrane transporter activity
biological_process GO:0009086 - methionine biosynthetic process
GO:0006865 - amino acid transport
GO:0055085 - transmembrane transport
GO:0003333 - amino acid transmembrane transport
GO:0015806 - S-methylmethionine transport
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
 B0260-MONOMER
ECOLIWIKI:
 b0260
INTERPRO:
 IPR002293
INTERPRO:
 IPR004841
INTERPRO:
 IPR004840
PANTHER:
 PTHR11785
PFAM:
 PF00324
PRIDE:
 Q47689
PROSITE:
 PS00218
REFSEQ:
 NP_414794
SMR:
 Q47689
UNIPROT:
 Q47689


Operon      
Name: mmuPM         
Operon arrangement:
Transcription unit        Promoter
 


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_466 275108 reverse nd [RS-EPT-CBR] [1]
  promoter mmuPp1 275119 forward Similarity to the consensus
Read more > 		[ICWHO] [2]
  promoter mmuPp6 275206 forward Similarity to the consensus
Read more > 		[ICWHO] [2]
  promoter mmuPp7 275285 forward Similarity to the consensus
Read more > 		[ICWHO] [2]
  promoter mmuPp5 275287 forward Similarity to the consensus
Read more > 		[ICWHO] [2]
  promoter insHp5 275298 reverse Similarity to the consensus
Read more > 		[ICWHO] [2]
  promoter mmuPp2 275315 forward Similarity to the consensus
Read more > 		[ICWHO] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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