RegulonDB RegulonDB 10.7: Gene Form
   

ecpR gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ecpR ecpA ykgL anti-terminator terminator ykgLp1 ykgLp1 matAp7 matAp7 matAp10 matAp10 matAp5 matAp5 matAp9 matAp9 matAp1 matAp1 matBp5 matBp5 matCp1 matCp1

Gene      
Name: ecpR    Texpresso search in the literature
Synonym(s): ECK0293, G6165, b0294, matA, ykgK
Genome position(nucleotides): 310746 <-- 311336 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
39.09
External database links:  
ASAP:
ABE-0001011
ECHOBASE:
EB4070
OU-MICROARRAY:
b0294
PORTECO:
matA
REGULONDB:
b0294
STRING:
511145.b0294
M3D: ecpR
COLOMBOS: ecpR
PortEco: b0294


Product      
Name: DNA-binding transcriptional dual regulator MatA
Synonym(s): EcpR, MatA, YkgK
Sequence: Get amino acid sequence Fasta Format
Regulator Family: LuxR/UhpA
Cellular location: cytosol
Molecular weight: 23.274
Isoelectric point: 9.78
Motif(s):
 
Type Positions Sequence
138 -> 196 KDIKKDKITDREMEIIRMTAQGMQPKSIARIENCSVKTVYTHRRNAEAKLYSKIYKLVQ
162 -> 181 PKSIARIENCSVKTVYTHRR
145 -> 187 ITDREMEIIRMTAQGMQPKSIARIENCSVKTVYTHRRNAEAKL
179 -> 179 H

 

Classification:
Multifun Terms (GenProtEC)  
  3 - regulation --> 3.1 - type of regulation --> 3.1.2 - transcriptional level
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0003677 - DNA binding
biological_process GO:0006355 - regulation of transcription, DNA-templated
GO:1902021 - regulation of bacterial-type flagellum-dependent cell motility
Note(s): Note(s): ...[more].
Evidence: [AIFS] Automated inference of function from sequence
[APPHINH] Assay of protein purified to homogeneity from its native host
[IEP] Inferred from expression pattern
Reference(s): [1] Lehti TA., et al., 2012
[2] Perez-Rueda E., et al., 2004
External database links:  
ECOCYC:
G6165-MONOMER
ECOLIWIKI:
b0294
INTERPRO:
IPR016032
INTERPRO:
IPR036388
INTERPRO:
IPR000792
MODBASE:
P71301
PFAM:
PF00196
PRIDE:
P71301
PRINTS:
PR00038
PROSITE:
PS50043
PROTEINMODELPORTAL:
P71301
REFSEQ:
NP_414828
SMART:
SM00421
SMR:
P71301
UNIPROT:
P71301


Operon      
Name: ecpR         
Operon arrangement:
Transcription unit        Promoter
 


Transcriptional Regulation      
Display Regulation             
Activated by: MatA


RNA cis-regulatory element    
Attenuation: Translational


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter matAp9 311432 reverse Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter matAp5 311446 reverse Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter matAp10 311460 reverse Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter matAp7 311482 reverse Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter ykgLp1 311939 forward Similarity to the consensus
Read more >
[ICWHO] [3]


Evidence    

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Lehti TA., Bauchart P., Dobrindt U., Korhonen TK., Westerlund-Wikstrom B., 2012, The fimbriae activator MatA switches off motility in Escherichia coli by repression of the flagellar master operon flhDC., Microbiology 158(Pt 6):1444-55

 [2] Perez-Rueda E., Collado-Vides J., Segovia L., 2004, Phylogenetic distribution of DNA-binding transcription factors in bacteria and archaea., Comput Biol Chem 28(5-6):341-50

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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