RegulonDB RegulonDB 10.8: Gene Form
   

rclC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

insEF1 insF1 ykgA rclC rclB ykgQ insE1 ykgBp9 ykgBp9 ykgBp7 ykgBp7 ykgBp4 ykgBp4 ykgBp3 ykgBp3 ykgBp10 ykgBp10

Gene      
Name: rclC    Texpresso search in the literature
Synonym(s): ECK0301, G6171, b0301, ykgB
Genome position(nucleotides): 317726 <-- 318319 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
44.95
External database links:  
ASAP:
ABE-0001038
ECHOBASE:
EB3349
OU-MICROARRAY:
b0301
PortEco:
ykgB
STRING:
511145.b0301
COLOMBOS: rclC


Product      
Name: reactive chlorine species resistance protein C
Synonym(s): RclC, YkgB
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 21.899
Isoelectric point: 6.351
Motif(s):
 
Type Positions Sequence
2 -> 182 EKYLHLLSRGDKIGLTLIRLSIAIVFMWIGLLKFVPYEADSITPFVANSPLMSFFYEHPEDYKQYLTHEGEYKPEARAWQTANNTYGFSNGLGVVEVIIALLVLANPVNRWLGLLGGLMAFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLVLKDTLMLAGAVMIMADSAREIL
16 -> 36 LTLIRLSIAIVFMWIGLLKFV
86 -> 106 TYGFSNGLGVVEVIIALLVLA
113 -> 133 LGLLGGLMAFTTPLVTLSFLI

 

Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes --> 5.6 - protection
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
biological_process GO:1901530 - response to hypochlorite
Note(s): Note(s): ...[more].
Evidence: [IMP] Inferred from mutant phenotype
Reference(s): [1] Parker BW., et al., 2013
External database links:  
ECOCYC:
G6171-MONOMER
ECOLIWIKI:
b0301
INTERPRO:
IPR007339
INTERPRO:
IPR016865
PANTHER:
PTHR40106
PFAM:
PF04224
PRIDE:
P75685
REFSEQ:
NP_414835
UNIPROT:
P75685


Operon      
Name: rclABC         
Operon arrangement:
Transcription unit        Promoter
rclABC
 


Transcriptional Regulation      
Display Regulation             
Activated by: RclR


Regulation by small RNA    
  Display Regulation
small RNA omrB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter ykgBp10 318334 reverse Similarity to the consensus
Read more >
[ICWHO] [2]
  promoter ykgBp3 318376 reverse Similarity to the consensus
Read more >
[ICWHO] [2]
  promoter ykgBp4 318397 reverse Similarity to the consensus
Read more >
[ICWHO] [2]
  promoter ykgBp7 318484 reverse Similarity to the consensus
Read more >
[ICWHO] [2]
  promoter ykgBp9 318525 reverse Similarity to the consensus
Read more >
[ICWHO] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Parker BW., Schwessinger EA., Jakob U., Gray MJ., 2013, The RclR protein is a reactive chlorine-specific transcription factor in Escherichia coli., J Biol Chem 288(45):32574-84

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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