RegulonDB RegulonDB 10.10: Gene Form
   

frmB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

frmA frmB yaiL terminator TSS_485 TSS_485

Gene      
Name: frmB    Texpresso search in the literature
Synonym(s): ECK0352, G6208, b0355, yaiM
Genome position(nucleotides): 377535 <-- 378368 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 48.56
External database links:  
ASAP:
 ABE-0001219
ECHOBASE:
 EB3080
ECOLIHUB:
 frmB
OU-MICROARRAY:
 b0355
STRING:
 511145.b0355
COLOMBOS: frmB


Product      
Name: S-formylglutathione hydrolase FrmB
Synonym(s): FrmB, YaiM
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 31.424
Isoelectric point: 6.224
Motif(s):
 
Type Positions Sequence
21 -> 268 SQSLKCEMNVGVYLPPKAANEKLPVLYWLSGLTCNEQNFITKSGMQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGFYLNATQAPWNEHYKMYDYIRNELPDLVMHHFPATAKKSISGHSMGGLGALVLALRNPDEYVSVSAFSPIVSPSQVPWGQQAFAAYLAENKDAWLDYDPVSLISQGQRVAEIMVDQGLSDDFYAEQLRTPNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIA

 
Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes --> 5.6 - protection --> 5.6.2 - detoxification
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0016787 - hydrolase activity
GO:0018738 - S-formylglutathione hydrolase activity
GO:0052689 - carboxylic ester hydrolase activity
biological_process GO:0046292 - formaldehyde metabolic process
GO:0046294 - formaldehyde catabolic process
Note(s): Note(s): ...[more].
External database links:  
DIP:
 DIP-11274N
ECOCYC:
 G6208-MONOMER
ECOLIWIKI:
 b0355
INTERPRO:
 IPR029058
INTERPRO:
 IPR014186
INTERPRO:
 IPR000801
MODBASE:
 P51025
PANTHER:
 PTHR10061
PFAM:
 PF00756
PRIDE:
 P51025
PRODB:
 PRO_000022695
REFSEQ:
 NP_414889
SMR:
 P51025
SWISSMODEL:
 P51025
UNIPROT:
 P51025


Operon      
Name: frmRAB         
Operon arrangement:
Transcription unit        Promoter
frmRAB


RNA cis-regulatory element    
Attenuation: Translational


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_485 378418 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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