RegulonDB RegulonDB 10.8: Gene Form
   

ybbO gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

cnoX ybbO ybbA tesA ybbP anti-anti-terminator anti-terminator terminator tesAp tesAp TSS_664 TSS_664 ybbOp4 ybbOp4 TSS_663 TSS_663 ybbNp2 ybbNp2 ybbNp1 ybbNp1 TSS_662 (cluster) TSS_662 (cluster) TSS_661 TSS_661

Gene      
Name: ybbO    Texpresso search in the literature
Synonym(s): ECK0487, G6269, b0493
Genome position(nucleotides): 518340 <-- 519149 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
54.32
External database links:  
ASAP:
ABE-0001709
ECHOBASE:
EB3050
OU-MICROARRAY:
b0493
PortEco:
ybbO
STRING:
511145.b0493
COLOMBOS: ybbO


Product      
Name: NADP+-dependent aldehyde reductase YbbO
Synonym(s): YbbO
Sequence: Get amino acid sequence Fasta Format
Molecular weight: 29.41
Isoelectric point: 9.151
Motif(s):
 
Type Positions Sequence
16 -> 204 KSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHSGIKVSLIEPGPIRTRFTDNVNQTQ
15 -> 41 QKSVLITGCSSGIGLESALELKRQGFH

 

Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
molecular_function GO:0016491 - oxidoreductase activity
GO:0008106 - alcohol dehydrogenase (NADP+) activity
biological_process GO:0055114 - oxidation-reduction process
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-48139N
ECOCYC:
G6269-MONOMER
ECOLIWIKI:
b0493
INTERPRO:
IPR020904
INTERPRO:
IPR036291
INTERPRO:
IPR002347
MODBASE:
P0AFP4
PANTHER:
PTHR24322
PFAM:
PF00106
PRIDE:
P0AFP4
PRINTS:
PR00081
PROSITE:
PS00061
REFSEQ:
NP_415026
SMR:
P0AFP4
UNIPROT:
P0AFP4


Operon      
Name: tesA-ybbO         
Operon arrangement:
Transcription unit        Promoter
tesA-ybbO


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_661 518264 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_662 (cluster) 518306 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [1]
  promoter ybbNp2 518568 reverse The sigma factor was determined
Read more >
[AIPP] [2]
  promoter TSS_663 518661 reverse nd [RS-EPT-CBR] [1]
  promoter ybbOp4 519329 reverse Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter TSS_664 519797 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [AIPP] Automated inference of promoter position

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [2] Zhao K., Liu M., Burgess RR., 2005, The global transcriptional response of Escherichia coli to induced sigma 32 protein involves sigma 32 regulon activation followed by inactivation and degradation of sigma 32 in vivo., J Biol Chem 280(18):17758-68

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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