RegulonDB

Gene
Name:	ssuC
Synonym(s):	ECK0925, G6476, b0934, ycbM
Genome position(nucleotides):	994041 <-- 994832 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	55.81
External database links:

ASAP:	ABE-0003175
ECHOBASE:	EB3469
OU-MICROARRAY:	b0934
PortEco:	ssuC
STRING:	511145.b0934
COLOMBOS:	ssuC

Product

Name:

aliphatic sulfonate ABC transporter membrane subunit

Synonym(s):

SsuC, YcbM

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

28.925

Isoelectric point:

10.028

Motif(s):

Type	Positions	Sequence
	14 -> 34	PWFLPVGIVAVWQLASSVGWL
	103 -> 122	MLRNVPHLALIPLVILWFGI
	126 -> 148	AKIFLVALGTLFPIYINTWHGIR
	218 -> 238	FLQTDVVVVAIILYALLGKLA
	58 -> 242	LWQHLAISSWRALIGFSIGGSLGLILGLISGLSRWGERLLDTSIQMLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREFLQTDVVVVAIILYALLGKLADVSA

Classification:

Multifun Terms (GenProtEC)
		1 - metabolism --> 1.8 - metabolism of other compounds --> 1.8.1 - phosphorous metabolism
		6 - cell structure --> 6.1 - membrane
		4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.m - ABC superfamily, membrane component
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0005887 - integral component of plasma membrane GO:0016021 - integral component of membrane GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
	molecular_function	GO:0022857 - transmembrane transporter activity GO:0042959 - alkanesulfonate transmembrane transporter activity
	biological_process	GO:0006790 - sulfur compound metabolic process GO:0055085 - transmembrane transport GO:0042918 - alkanesulfonate transport

Note(s):

Note(s): ...[more].

Reference(s):

[1] Jindal S., et al., 2019

External database links:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

PFAM:

PRIDE:

PROSITE:

REFSEQ:

UNIPROT:

Operon

Name:

ssuEADCB

Operon arrangement:

Transcription unit	Promoter
ssuEADCB	ssuEp

Transcriptional Regulation
	Display Regulation
Activated by:	Cbl, FNR, IHF
Repressed by:	CysB, IHF

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	TSS_1245 (cluster)	991200	forward	For this promoter, there is a cluster of 2 transcription start sites,in the interval 991200 to 991201, where the highest frequency is at position 990423. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[2]
promoter	TSS_1246	991492	forward	nd	[RS-EPT-CBR]	[2]
promoter	ssuBp3	994141	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 5.154. P-value: 2.653e-6 Read more >	[ICWHO]	[3]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates
[ICWHO] Inferred computationally without human oversight

Reference(s)
[1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195
[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.
[3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78