RegulonDB RegulonDB 10.8: Gene Form
   

ssuC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

pepN ssuD ssuC ssuB ssuA CRP ssuBp3 ssuBp3 TSS_1246 TSS_1246 TSS_1245 (cluster) TSS_1245 (cluster)

Gene      
Name: ssuC    Texpresso search in the literature
Synonym(s): ECK0925, G6476, b0934, ycbM
Genome position(nucleotides): 994041 <-- 994832 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
55.81
External database links:  
ASAP:
ABE-0003175
ECHOBASE:
EB3469
OU-MICROARRAY:
b0934
PortEco:
ssuC
STRING:
511145.b0934
COLOMBOS: ssuC


Product      
Name: aliphatic sulfonate ABC transporter membrane subunit
Synonym(s): SsuC, YcbM
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 28.925
Isoelectric point: 10.028
Motif(s):
 
Type Positions Sequence
14 -> 34 PWFLPVGIVAVWQLASSVGWL
103 -> 122 MLRNVPHLALIPLVILWFGI
126 -> 148 AKIFLVALGTLFPIYINTWHGIR
218 -> 238 FLQTDVVVVAIILYALLGKLA
58 -> 242 LWQHLAISSWRALIGFSIGGSLGLILGLISGLSRWGERLLDTSIQMLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREFLQTDVVVVAIILYALLGKLADVSA

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.8 - metabolism of other compounds --> 1.8.1 - phosphorous metabolism
  6 - cell structure --> 6.1 - membrane
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.m - ABC superfamily, membrane component
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
molecular_function GO:0022857 - transmembrane transporter activity
GO:0042959 - alkanesulfonate transmembrane transporter activity
biological_process GO:0006790 - sulfur compound metabolic process
GO:0055085 - transmembrane transport
GO:0042918 - alkanesulfonate transport
Note(s): Note(s): ...[more].
Reference(s): [1] Jindal S., et al., 2019
External database links:  
ECOCYC:
YCBM-MONOMER
ECOLIWIKI:
b0934
INTERPRO:
IPR035906
INTERPRO:
IPR000515
PFAM:
PF00528
PRIDE:
P75851
PROSITE:
PS50928
REFSEQ:
NP_415454
UNIPROT:
P75851


Operon      
Name: ssuEADCB         
Operon arrangement:
Transcription unit        Promoter
ssuEADCB


Transcriptional Regulation      
Display Regulation             
Activated by: Cbl, FNR, IHF
Repressed by: CysB, IHF


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1245 (cluster) 991200 forward For this promoter, there
Read more >
[RS-EPT-CBR] [2]
  promoter TSS_1246 991492 forward nd [RS-EPT-CBR] [2]
  promoter ssuBp3 994141 reverse Similarity to the consensus
Read more >
[ICWHO] [3]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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