Gene
Name:	zapC
Synonym(s):	ECK0937, G6486, b0946, ycbW
Genome position(nucleotides):	1005952 --> 1006494 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	49.36
External database links:

ASAP:	ABE-0003204
ECHOBASE:	EB3479
OU-MICROARRAY:	b0946
PORTECO:	ycbW
REGULONDB:	b0946
STRING:	511145.b0946
M3D:	zapC
COLOMBOS:	zapC
PortEco:	b0946

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	ycbWp6	1005850	forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 5.016. P-value: 6.252e-5 Read more >	[ICWHO]	[4]
promoter	TSS_1247 (cluster)	1005852	forward	For this promoter, there is a cluster of 2 transcription start sites,in the interval 1005852 to 1005853, where the highest frequency is at position 1005075. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[5]
promoter	ycbWp4	1005890	forward	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 4.084. P-value: 2.895e-5 Read more >	[ICWHO]	[4]
promoter	TSS_1248	1008970	forward	nd	[RS-EPT-CBR]	[5]

Evidence
[ICWHO] Inferred computationally without human oversight
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Durand-Heredia JM., Yu HH., De Carlo S., Lesser CF., Janakiraman A., 2011, Identification and characterization of ZapC, a stabilizer of the FtsZ ring in Escherichia coli., J Bacteriol 193(6):1405-13
[2] Hale CA., Shiomi D., Liu B., Bernhardt TG., Margolin W., Niki H., de Boer PA., 2011, Identification of Escherichia coli ZapC (YcbW) as a component of the division apparatus that binds and bundles FtsZ polymers., J Bacteriol 193(6):1393-404
[3] Krupka M., Rowlett VW., Morado D., Vitrac H., Schoenemann K., Liu J., Margolin W., 2017, Escherichia coli FtsA forms lipid-bound minirings that antagonize lateral interactions between FtsZ protofilaments., Nat Commun 8:15957
[4] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78
[5] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

RNA cis-regulatory element

Attenuation:	Transcriptional