RegulonDB RegulonDB 10.8: Gene Form
   

pqiC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

pqiB pqiA pqiC rmf CRP ppGpp terminator anti-terminator rmfp rmfp rmfp4 rmfp4 rmfp5 rmfp5

Gene      
Name: pqiC    Texpresso search in the literature
Synonym(s): ECK0943, G6492, b0952, ymbA
Genome position(nucleotides): 1014896 --> 1015459 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
52.13
External database links:  
ASAP:
ABE-0003223
ECHOBASE:
EB3483
OU-MICROARRAY:
b0952
PortEco:
ymbA
STRING:
511145.b0952
COLOMBOS: pqiC


Product      
Name: intermembrane transport lipoprotein PqiC
Synonym(s): PqiC, YmbA
Sequence: Get amino acid sequence Fasta Format
Cellular location: outer membrane,periplasmic space
Molecular weight: 20.634
Isoelectric point: 5.893
Motif(s):
 
Type Positions Sequence
26 -> 180 YQLPVVQSGTQSTASQGNRLLWVEQVTVPDYLAGNGVVYQTSDVKYVIANNNLWASPLDQQLRNTLVANLSTQLPGWVVASQPLGSAQDTLNVTVTEFNGRYDGKVIVSGEWLLNHQGQLIKRPFRLEGVQTQDGYDEMVKVLAGVWSQEAASIA
1 -> 15 MKKWLVTIAALWLAG
16 -> 187 CSSGEINKNYYQLPVVQSGTQSTASQGNRLLWVEQVTVPDYLAGNGVVYQTSDVKYVIANNNLWASPLDQQLRNTLVANLSTQLPGWVVASQPLGSAQDTLNVTVTEFNGRYDGKVIVSGEWLLNHQGQLIKRPFRLEGVQTQDGYDEMVKVLAGVWSQEAASIAQEIKRLP

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0009279 - cell outer membrane
GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
GO:0036406 - anchored component of periplasmic side of cell outer membrane
molecular_function GO:0005515 - protein binding
GO:0042802 - identical protein binding
biological_process GO:0120009 - intermembrane lipid transfer
GO:0046907 - intracellular transport
GO:0061024 - membrane organization
Note(s): Note(s): ...[more].
Evidence: [IGI] Inferred from genetic interaction
Reference(s): [1] Ekiert DC., et al., 2017
[2] Nakayama T., et al., 2017
External database links:  
DIP:
DIP-48221N
ECOCYC:
G6492-MONOMER
ECOLIWIKI:
b0952
INTERPRO:
IPR005586
PFAM:
PF03886
PRIDE:
P0AB10
PROSITE:
PS51257
REFSEQ:
NP_415472
SMR:
P0AB10
UNIPROT:
P0AB10


Operon      
Name: pqiABC         
Operon arrangement:
Transcription unit        Promoter
pqiABC
pqiABC
ymbA


Transcriptional Regulation      
Display Regulation             
Activated by: MarA, SoxS


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter rmfp5 1015503 forward Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter rmfp4 1015532 forward Similarity to the consensus
Read more >
[ICWHO] [3]


Evidence    

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Ekiert DC., Bhabha G., Isom GL., Greenan G., Ovchinnikov S., Henderson IR., Cox JS., Vale RD., 2017, Architectures of Lipid Transport Systems for the Bacterial Outer Membrane., Cell 169(2):273-285.e17

 [2] Nakayama T., Zhang-Akiyama QM., 2017, pqiABC and yebST, Putative mce Operons of Escherichia coli, Encode Transport Pathways and Contribute to Membrane Integrity., J Bacteriol 199(1)

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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