RegulonDB RegulonDB 10.9: Gene Form
   

gfcA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

insAB4 gfcB insB4 gfcA insA4 gfcC TSS_1308 TSS_1308 gfcAp1 gfcAp1

Gene      
Name: gfcA    Texpresso search in the literature
Synonym(s): ECK0978, G6508, b0987, ymcD
Genome position(nucleotides): 1049439 <-- 1049744 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
57.52
External database links:  
ASAP:
ABE-0003325
ECHOBASE:
EB3496
ECOLIHUB:
gfcA
OU-MICROARRAY:
b0987
STRING:
511145.b0987
COLOMBOS: gfcA


Product      
Name: threonine-rich inner membrane protein GfcA
Synonym(s): GfcA, YmcD
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 9.507
Isoelectric point: 6.504
Motif(s):
 
Type Positions Sequence
60 -> 80 VGTATVVGVATAVGVATLAVV
1 -> 21 MKHKLSAILMAFMLTTPAAFA
22 -> 101 APEATNGTEATTGTTGTTTTTTGATTTATTTGGVAAGAVGTATVVGVATAVGVATLAVVAANDSGDGGSHNTSTTTSTTR
15 -> 100 TTPAAFAAPEATNGTEATTGTTGTTTTTTGATTTATTTGGVAAGAVGTATVVGVATAVGVATLAVVAANDSGDGGSHNTSTTTSTT

 

Classification:
Multifun Terms (GenProtEC)  
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-12710N
ECOCYC:
G6508-MONOMER
ECOLIWIKI:
b0987
PRIDE:
P75885
PRODB:
PRO_000022768
REFSEQ:
NP_415507
UNIPROT:
P75885


Operon      
Name: gfcA         
Operon arrangement:
Transcription unit        Promoter
gfcA


Transcriptional Regulation      
Display Regulation             
Repressed by: YjjQ


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter gfcAp1 1049834 reverse Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter TSS_1308 1049998 reverse nd [RS-EPT-CBR] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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