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Gene | ![]() ![]() |
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Name: | efeU ![]() |
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Synonym(s): | ECK1007, G6525, b1016, b1017, b4490, ycdN | |
Type: | Pseudo Gene | |
Genome position(nucleotides): | 1081356 --> 1082185 Genome Browser | |
Strand: | forward | |
Sequence: | Get nucleotide sequence FastaFormat | |
GC content %: |
54.22 | |
Note(s): | efeU_1 and efeU_2 are two fragments of a pseudogene (efeU*). A functional efeU (ycdN) gene in E. coli Nissle 1917 encodes a ferrous iron permease 16987175; a functional efeUOB operon in enterohaemorrhagic E. coli O157:H7 encodes a tripartite, acid-induced Fe(II) transport system 17627767. Analysis of transcriptional efe-lacZ fusions suggest that efeU*OB forms an operon in E. coli K-12 which is transcribed from a promoter located upstream of efeU* 17627767. efeU* in E. coli K-12 is disrupted by a frameshift mutation leaving the efeU_1 and efeU_2 fragments nonfunctional; EfeO and EfeB are produced despite the frameshift mutation 16987175 efeU*OB transcription in E. coli K-12 is subject to Fe(II)-Fur control in response to iron McHugh JP,2003. 16987175. 17627767. The efeU*OB operon is induced at acid pH and subject to CpxAR dependent repression at alkaline pH 17627767. Deletion of efeU*, efeO, or efeB does not result in any growth defect under iron limitation 17627767 Low copy-number expression of a 'corrected' efeUOB operon in an E. coli K-12 strain lacking lacking all known iron-transport pathways confers a growth advantage under iron restricted conditions 17627767. Expression of EfeU decreases in early osmotic upshift (0.4 M NaCl) 12218039 efeU_2 expression decreases under anaerobic conditions in both a wild-type and a Δfur mutant strain Kang Y,2005 efe: elemental ferrous iron uptake 16987175. |
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Reference(s): | [1] Masse E., et al., 2005 [2] Ren D., et al., 2004 |
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External database links: | ||
ASAP: |
ABE-0003443 | |
ASAP: |
ABE-0285091 | |
ASAP: |
ABE-0003441 | |
ECHOBASE: |
EB3620 | |
INTERPRO: |
IPR004923 | |
INTERPRO: |
IPR005217 | |
OU-MICROARRAY: |
b1016 | |
OU-MICROARRAY: |
b1017 | |
PortEco: |
efeU_2 | |
PortEco: |
efeU_1 | |
UNIPROT: |
P75901 | |
COLOMBOS: | efeU |
Product | ![]() ![]() |
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Name: | inactive ferrous iron permease EfeU | ||||||
Sequence: | Get amino acid sequence Fasta Format | ||||||
Isoelectric point: | 11.711 | ||||||
Motif(s): | |||||||
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Classification: |
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External database links: | |||||||
ECOCYC: |
MONOMER0-4386 | ||||||
UNIPROT: |
P75901 | ||||||
Elements in the selected gene context region unrelated to any object in RegulonDB | ![]() ![]() |
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Type | Name | Post Left | Post Right | Strand | Notes | Evidence (Confirmed, Strong, Weak) | References | |
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promoter | efeOp2 | 1082154 | forward |
Similarity to the consensus Read more > |
[ICWHO] | [3] | ||
promoter | efeOp1 | 1082243 | forward |
Similarity to the consensus Read more > |
[ICWHO] | [3] |
Reference(s) |
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