RegulonDB RegulonDB 10.8: Gene Form
   

solA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

solA bssS yceO anti-anti-terminator anti-terminator terminator TSS_1333 TSS_1333 solAp solAp yceOp7 yceOp7 yceOp8 yceOp8 yceOp1 yceOp1

Gene      
Name: solA    Texpresso search in the literature
Synonym(s): ECK1044, G6556, b1059
Genome position(nucleotides): 1119468 <-- 1120586 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
52.46
External database links:  
ASAP:
ABE-0003590
ECHOBASE:
EB2535
OU-MICROARRAY:
b1059
PortEco:
solA
STRING:
511145.b1059
COLOMBOS: solA


Product      
Name: N-methyl-L-tryptophan oxidase
Synonym(s): SolA
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 40.902
Isoelectric point: 5.003
Motif(s):
 
Type Positions Sequence
4 -> 34 DLIIIGSGSVGAAAGYYATRAGLNVLMTDAH

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0008115 - sarcosine oxidase activity
GO:0016491 - oxidoreductase activity
GO:0016647 - oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor
GO:0050131 - N-methyl-L-amino-acid oxidase activity
GO:0050660 - flavin adenine dinucleotide binding
biological_process GO:0006974 - cellular response to DNA damage stimulus
GO:0055114 - oxidation-reduction process
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
SARCOX-MONOMER
ECOLIWIKI:
b1059
INTERPRO:
IPR023493
INTERPRO:
IPR006076
INTERPRO:
IPR036188
MODBASE:
P40874
PDB:
2UZZ
PFAM:
PF01266
PRIDE:
P40874
PRODB:
PRO_000023967
REFSEQ:
NP_415577
SMR:
P40874
SWISSMODEL:
P40874
UNIPROT:
P40874


Operon      
Name: solA-yceO         
Operon arrangement:
Transcription unit        Promoter
solA-yceO


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yceOp1 1119511 reverse Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter yceOp8 1119623 reverse Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter yceOp7 1119632 reverse Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter TSS_1333 1120934 reverse nd [RS-EPT-CBR] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


RegulonDB