RegulonDB

Gene
Name:	zntB
Synonym(s):	ECK1339, G6674, b1342, ydaN
Genome position(nucleotides):	1408050 --> 1409033 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	51.93
External database links:

ASAP:	ABE-0004508
ECHOBASE:	EB3139
OU-MICROARRAY:	b1342
PortEco:	ydaN
STRING:	511145.b1342
COLOMBOS:	zntB

Product

Name:

Zn²⁺:H⁺ symporter

Synonym(s):

YdaN, ZntB

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

36.612

Isoelectric point:

4.952

Motif(s):

Type	Positions	Sequence
	39 -> 323	HPCWLHLNYVHHDSAQWLATTPLLPNNVRDALAGESTRPRVSRLGEGTLITLRCINGSTDERPDQLVAMRVYMDGRLIVSTRQRKVLALDDVVSDLEEGTGPTDCGGWLVDVCDALTDHSSEFIEQLHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPWMSDDQRRRMQDIADRLGRGLDEIDACIARTGVMADEIAQVMQENLARRTYTMSLMAMVFLPSTFLTGLFGVNLGGIPGGGWQFGFSIFCILLVVLIGGVALWLHR
	272 -> 294	LMAMVFLPSTFLTGLFGVNLGGI
	299 -> 321	WQFGFSIFCILLVVLIGGVALWL

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		4 - transport
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0005887 - integral component of plasma membrane GO:0016021 - integral component of membrane
	molecular_function	GO:0005515 - protein binding GO:0015295 - solute:proton symporter activity GO:0005385 - zinc ion transmembrane transporter activity GO:0015087 - cobalt ion transmembrane transporter activity GO:0015095 - magnesium ion transmembrane transporter activity GO:0022883 - zinc efflux transmembrane transporter activity GO:0000287 - magnesium ion binding GO:0050897 - cobalt ion binding
	biological_process	GO:0071578 - zinc ion import across plasma membrane GO:0006811 - ion transport GO:0006824 - cobalt ion transport GO:0006829 - zinc ion transport GO:0071577 - zinc ion transmembrane transport GO:1902600 - proton transmembrane transport GO:1903830 - magnesium ion transmembrane transport

Note(s):

Note(s): ...[more].

Reference(s):

[1] Paradis-Bleau C., et al., 2014

External database links:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

PDB:

PFAM:

PRIDE:

PRODB:

REFSEQ:

SMR:

UNIPROT:

Operon

Name:

zntB

Operon arrangement:

Transcription unit	Promoter
zntB	zntBp

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	TSS_1766	1408027	forward	nd	[RS-EPT-CBR]	[2]
promoter	TSS_1768	1409131	forward	nd	[RS-EPT-CBR]	[2]
promoter	TSS_1769	1409133	forward	nd	[RS-EPT-CBR]	[2]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Paradis-Bleau C., Kritikos G., Orlova K., Typas A., Bernhardt TG., 2014, A genome-wide screen for bacterial envelope biogenesis mutants identifies a novel factor involved in cell wall precursor metabolism., PLoS Genet 10(1):e1004056
[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Reference(s)

[1] Paradis-Bleau C., Kritikos G., Orlova K., Typas A., Bernhardt TG., 2014, A genome-wide screen for bacterial envelope biogenesis mutants identifies a novel factor involved in cell wall precursor metabolism., PLoS Genet 10(1):e1004056

[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.