RegulonDB RegulonDB 10.8: Gene Form
   

zntB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

zntB fnrS ynaN FNR TSS_1769 TSS_1769 TSS_1768 TSS_1768 fnrSp fnrSp TSS_1766 TSS_1766 zntBp zntBp

Gene      
Name: zntB    Texpresso search in the literature
Synonym(s): ECK1339, G6674, b1342, ydaN
Genome position(nucleotides): 1408050 --> 1409033 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
51.93
External database links:  
ASAP:
ABE-0004508
ECHOBASE:
EB3139
OU-MICROARRAY:
b1342
PortEco:
ydaN
STRING:
511145.b1342
COLOMBOS: zntB


Product      
Name: Zn2+:H+ symporter
Synonym(s): YdaN, ZntB
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 36.612
Isoelectric point: 4.952
Motif(s):
 
Type Positions Sequence
39 -> 323 HPCWLHLNYVHHDSAQWLATTPLLPNNVRDALAGESTRPRVSRLGEGTLITLRCINGSTDERPDQLVAMRVYMDGRLIVSTRQRKVLALDDVVSDLEEGTGPTDCGGWLVDVCDALTDHSSEFIEQLHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPWMSDDQRRRMQDIADRLGRGLDEIDACIARTGVMADEIAQVMQENLARRTYTMSLMAMVFLPSTFLTGLFGVNLGGIPGGGWQFGFSIFCILLVVLIGGVALWLHR
272 -> 294 LMAMVFLPSTFLTGLFGVNLGGI
299 -> 321 WQFGFSIFCILLVVLIGGVALWL

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0005515 - protein binding
GO:0015295 - solute:proton symporter activity
GO:0005385 - zinc ion transmembrane transporter activity
GO:0015087 - cobalt ion transmembrane transporter activity
GO:0015095 - magnesium ion transmembrane transporter activity
GO:0022883 - zinc efflux transmembrane transporter activity
GO:0000287 - magnesium ion binding
GO:0050897 - cobalt ion binding
biological_process GO:0071578 - zinc ion import across plasma membrane
GO:0006811 - ion transport
GO:0006824 - cobalt ion transport
GO:0006829 - zinc ion transport
GO:0071577 - zinc ion transmembrane transport
GO:1902600 - proton transmembrane transport
GO:1903830 - magnesium ion transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Paradis-Bleau C., et al., 2014
External database links:  
DIP:
DIP-48038N
ECOCYC:
G6674-MONOMER
ECOLIWIKI:
b1342
INTERPRO:
IPR023714
INTERPRO:
IPR002523
PDB:
5N9Y
PFAM:
PF01544
PRIDE:
P64423
PRODB:
PRO_000024250
REFSEQ:
NP_415858
SMR:
P64423
UNIPROT:
P64423


Operon      
Name: zntB         
Operon arrangement:
Transcription unit        Promoter
zntB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1766 1408027 forward nd [RS-EPT-CBR] [2]
  promoter TSS_1768 1409131 forward nd [RS-EPT-CBR] [2]
  promoter TSS_1769 1409133 forward nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Paradis-Bleau C., Kritikos G., Orlova K., Typas A., Bernhardt TG., 2014, A genome-wide screen for bacterial envelope biogenesis mutants identifies a novel factor involved in cell wall precursor metabolism., PLoS Genet 10(1):e1004056

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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